7YHK

Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5

Summary for 7YHK

• Entry DOI: 10.2210/pdb7yhk/pdb
• EMDB information: 33831
• Descriptor: 12H5 light chain, 12H5 heavy chain, Hemagglutinin, ... (5 entities in total)
• Functional Keywords: influenza virus, hemagglutinin, neutralizing antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus (A/Beijing/262/1995(H1N1)); More
• Total number of polymer chains: 3
• Total formula weight: 88640.76

Authors

Zheng, Q.,Li, S.,Li, T.,Xue, W.,Sun, H. (deposition date: 2022-07-13, release date: 2022-08-17, Last modification date: 2023-07-19)

• Primary citation: Li, T.,Chen, J.,Zheng, Q.,Xue, W.,Zhang, L.,Rong, R.,Zhang, S.,Wang, Q.,Hong, M.,Zhang, Y.,Cui, L.,He, M.,Lu, Z.,Zhang, Z.,Chi, X.,Li, J.,Huang, Y.,Wang, H.,Tang, J.,Ying, D.,Zhou, L.,Wang, Y.,Yu, H.,Zhang, J.,Gu, Y.,Chen, Y.,Li, S.,Xia, N.; Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses.; Nat Commun, 13:5182-5182, 2022; PubMed: 36056024; DOI: 10.1038/s41467-022-32926-5

Experimental method

ELECTRON MICROSCOPY (3.14 Å)