7YHK
Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | 12H5 light chain | polymer | 117 | 12990.6 | 1 | Mus musculus | ||
| 2 | B (H) | 12H5 heavy chain | polymer | 113 | 12249.5 | 1 | Mus musculus | ||
| 3 | C (A) | Hemagglutinin | polymer | 555 | 62091.5 | 1 | UniProt (Q6WG01) Pfam (PF00509) | Influenza A virus (A/Beijing/262/1995(H1N1)) | |
| 4 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, F, G, H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A: 5 - 504 (UniProt: Q6WG01)
| PDB | External Database | Details |
|---|---|---|
| Met -38 | - | initiating methionine |
| Leu -37 | - | expression tag |
| Leu -36 | - | expression tag |
| Val -35 | - | expression tag |
| Asn -34 | - | expression tag |
| Gln -33 | - | expression tag |
| Ser -32 | - | expression tag |
| His -31 | - | expression tag |
| Gln -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Phe -28 | - | expression tag |
| Asn -27 | - | expression tag |
| Lys -26 | - | expression tag |
| Glu -25 | - | expression tag |
| His -24 | - | expression tag |
| Thr -23 | - | expression tag |
| Ser -22 | - | expression tag |
| Lys -21 | - | expression tag |
| Met -20 | - | expression tag |
| Val -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ala -17 | - | expression tag |
| Ile -16 | - | expression tag |
| Val -15 | - | expression tag |
| Leu -14 | - | expression tag |
| Tyr -13 | - | expression tag |
| Val -12 | - | expression tag |
| Leu -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Ala -8 | - | expression tag |
| Ala -7 | - | expression tag |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Asp 1 | - | expression tag |
| Leu 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Ser 4 | - | expression tag |
| Ser 505 | - | expression tag |
| Gly 506 | - | expression tag |
| Arg 507 | - | expression tag |
| Leu 508 | - | expression tag |
| Val 509 | - | expression tag |
| Pro 510 | - | expression tag |
| Arg 511 | - | expression tag |
| Gly 512 | - | expression tag |
| Ser 513 | - | expression tag |
| Pro 514 | - | expression tag |
| Gly 515 | - | expression tag |
| Ser 516 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87331.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 88640.8 |
