7RDH

Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin

Summary for 7RDH

• Entry DOI: 10.2210/pdb7rdh/pdb
• Descriptor: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, De novo designed protein H3mb, ... (7 entities in total)
• Functional Keywords: de novo design, mini protein, ha stem binder, viral protein, viral protein-de novo protein complex, viral protein/de novo protein
• Biological source: Influenza A virus (strain A/Hong Kong/1/1968 H3N2); More
• Total number of polymer chains: 8
• Total formula weight: 211393.56

Authors

Kadam, R.U.,Wilson, I.A. (deposition date: 2021-07-09, release date: 2022-05-04, Last modification date: 2023-10-18)

• Primary citation: Cao, L.,Coventry, B.,Goreshnik, I.,Huang, B.,Sheffler, W.,Park, J.S.,Jude, K.M.,Markovic, I.,Kadam, R.U.,Verschueren, K.H.G.,Verstraete, K.,Walsh, S.T.R.,Bennett, N.,Phal, A.,Yang, A.,Kozodoy, L.,DeWitt, M.,Picton, L.,Miller, L.,Strauch, E.M.,DeBouver, N.D.,Pires, A.,Bera, A.K.,Halabiya, S.,Hammerson, B.,Yang, W.,Bernard, S.,Stewart, L.,Wilson, I.A.,Ruohola-Baker, H.,Schlessinger, J.,Lee, S.,Savvides, S.N.,Garcia, K.C.,Baker, D.; Design of protein-binding proteins from the target structure alone.; Nature, 605:551-560, 2022; PubMed: 35332283; DOI: 10.1038/s41586-022-04654-9

Experimental method

X-RAY DIFFRACTION (2.75 Å)