PDB: 376 resultsInfo pagesStatus searchChemie searchBIRD

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2MNG	Apo Structure of human HCN4 CNBD solved by NMR Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Authors: Akimoto, M, Zhang, Z, Boulton, S, Selvaratnam, R, VanSchouwen, B, Gloyd, M, Accili, E.A, Lange, O.F, Melacini, G. Deposit date: 2014-04-03 Release date: 2014-06-04 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP. J.Biol.Chem., 289, 2014
2MHF	Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel Descriptor: Uncharacterized protein Authors: Li, Q, Ng, H. Deposit date: 2013-11-21 Release date: 2014-04-02 Last modified: 2022-08-24 Method: SOLUTION NMR Cite: Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel. J.Struct.Biol., 186, 2014
2KXL	Solution structure of a bacterial cyclic nucleotide-activated K+ channel binding domain in the unliganded state Descriptor: Cyclic nucleotide-gated potassium channel mll3241 Authors: Schunke, S, Stoldt, M, Willbold, D. Deposit date: 2010-05-10 Release date: 2011-04-20 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel. Proc.Natl.Acad.Sci.USA, 108, 2011
2Z69	Crystal Structure of the sensor domain of the transcriptional regulator DNR from Pseudomonas aeruginosa Descriptor: DNR protein Authors: Giardina, G, Johnson, K.A, Di Matteo, A. Deposit date: 2007-07-24 Release date: 2008-03-18 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR. J.Mol.Biol., 378, 2008
2K0G	Solution Structure of a Bacterial Cyclic Nucleotide-Activated K+ Channel Binding Domain in Complex with cAMP Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Mll3241 protein Authors: Schunke, S, Stoldt, M, Willbold, D. Deposit date: 2008-02-02 Release date: 2009-02-10 Last modified: 2022-03-16 Method: SOLUTION NMR Cite: Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP. Embo Rep., 10, 2009
5H5O	A cyclic-GMP-dependent signalling pathway regulates bacterial phytopathogenesis Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Diguanylate cyclase Authors: Chin, K.H, Chou, S.-H. Deposit date: 2016-11-08 Release date: 2017-05-24 Method: X-RAY DIFFRACTION (2.122 Å) Cite: A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis EMBO J., 32, 2013
3UKN	Structure of the C-linker/CNBHD of zELK channels in C 2 2 21 space group Descriptor: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family Authors: Brelidze, T.I. Deposit date: 2011-11-09 Release date: 2012-01-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of the carboxy-terminal region of a KCNH channel. Nature, 481, 2012
3UKT	Structure of the C-linker/CNBHD of zELK channels in P1 21 1 space group Descriptor: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family Authors: Brelidze, T.I. Deposit date: 2011-11-09 Release date: 2012-01-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of the carboxy-terminal region of a KCNH channel. Nature, 481, 2012
5J3U	Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Protein Kinase A Authors: El Bakkouri, M, Walker, J.R, Tempel, W, Loppnau, P, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lin, L, Structural Genomics Consortium (SGC) Deposit date: 2016-03-31 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP To Be Published
5J48	PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-pCPT-cGMP Descriptor: 1,2-ETHANEDIOL, 2-amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-3,9-dihydro-6H-purin-6-one, CALCIUM ION, ... Authors: Campbell, J.C, Sankaran, B, Kim, C.W. Deposit date: 2016-03-31 Release date: 2017-04-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Structural Basis of Analog Specificity in PKG I and II. ACS Chem. Biol., 12, 2017
2D93	Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6 Descriptor: Rap guanine nucleotide exchange factor 6 Authors: Inoue, K, Muto, Y, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-12-08 Release date: 2006-06-08 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6 to be published
5JD7	PKG I's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with PET-cGMP Descriptor: 3-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-6-phenyl-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one, cGMP-dependent protein kinase 1 Authors: Campbell, J.C, Sankaran, B, Kim, C.W. Deposit date: 2016-04-15 Release date: 2017-08-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.749 Å) Cite: Structural Basis of Analog Specificity in PKG I and II. ACS Chem. Biol., 12, 2017
5JAX	PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-Br-cGMP Descriptor: 2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-1,9-dihydro-6H-purin-6-one, CALCIUM ION, SODIUM ION, ... Authors: Campbell, J.C, Sankaran, B, Kim, C.W. Deposit date: 2016-04-12 Release date: 2017-04-19 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.486 Å) Cite: Structural Basis of Analog Specificity in PKG I and II. ACS Chem. Biol., 12, 2017
5JIX	PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-Br-cGMP Descriptor: 1,2-ETHANEDIOL, 2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-1,9-dihydro-6H-purin-6-one, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... Authors: Campbell, J.C, Kim, C.W. Deposit date: 2016-04-22 Release date: 2017-05-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Structural Basis of Analog Specificity in PKG I and II. ACS Chem. Biol., 12, 2017
3U10	Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Authors: Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. Deposit date: 2011-09-29 Release date: 2011-10-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J.Biol.Chem., 286, 2011
3U0Z	Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Authors: Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. Deposit date: 2011-09-29 Release date: 2011-10-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J.Biol.Chem., 286, 2011
3U11	Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Authors: Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. Deposit date: 2011-09-29 Release date: 2011-10-26 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J.Biol.Chem., 286, 2011
3UKV	Structure of the C-linker/CNBHD of zELK channels in P 1 21 1 space group, crystallized in the presence of cAMP Descriptor: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family Authors: Brelidze, T.I. Deposit date: 2011-11-09 Release date: 2012-01-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the carboxy-terminal region of a KCNH channel. Nature, 481, 2012
7MBJ	Crystal structure of cGMP dependent protein kinase I alpha (PKG I alpha)CNB-A domain with R177Q mutation Descriptor: cGMP-dependent protein kinase 1 Authors: Kim, J.J, Casteel, D.E, Kim, C. Deposit date: 2021-03-31 Release date: 2022-05-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.26 Å) Cite: An auto-inhibited state of protein kinase G and implications for selective activation. Elife, 11, 2022
7LZ4	Crystal structure of A211D mutant of Protein Kinase A RIa subunit, a Carney Complex mutation Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed Authors: Del Rio, J, Wu, J, Taylor, S.S. Deposit date: 2021-03-08 Release date: 2021-05-26 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4.155 Å) Cite: Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations. Proc.Natl.Acad.Sci.USA, 118, 2021
3MDP	Crystal structure of a Putative Cyclic nucleotide-binding protein (Gmet_1532) from Geobacter metallireducens GS-15 at 1.90 A resolution Descriptor: 1,2-ETHANEDIOL, Cyclic nucleotide-binding domain (CNMP-BD) protein, SUCCINIC ACID Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2010-03-30 Release date: 2010-05-19 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of a Putative Cyclic nucleotide-binding protein (Gmet_1532) from Geobacter metallireducens GS-15 at 1.90 A resolution To be published
3OCP	Crystal structure of cAMP bound cGMP-dependent protein kinase(92-227) Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PRKG1 protein Authors: Kim, J.J, Huang, G, Kwon, T.K, Zwart, P, Headd, J, Kim, C. Deposit date: 2010-08-10 Release date: 2011-05-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding Plos One, 6, 2011
3OD0	Crystal structure of cGMP bound cGMP-dependent protein kinase(92-227) Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, PRKG1 protein Authors: Kim, J.J, Huang, G, Kwon, T.K, Zwart, P, Headd, J, Kim, C. Deposit date: 2010-08-10 Release date: 2011-05-11 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding Plos One, 6, 2011
5D1I	Structure of Cyclic nucleotide-binding-like protein from Brucella abortus bv. 1 str. 9-941 Descriptor: Cyclic nucleotide-binding protein Authors: He, Z, Dong, J, Li, X, Gao, Y. Deposit date: 2015-08-04 Release date: 2015-09-09 Last modified: 2016-01-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of cyclic nucleotide-binding-like protein from Brucella abortus Biochem.Biophys.Res.Commun., 468, 2015
4OFF	Crystal structure of apo carboxy cGMP binding domain of Plasmodium falciparum PKG Descriptor: CGMP-dependent protein kinase, SULFATE ION Authors: Kim, J.J, Sanabria figueroa, E, Kim, C. Deposit date: 2014-01-14 Release date: 2015-01-21 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.888 Å) Cite: Crystal Structures of the Carboxyl cGMP Binding Domain of the Plasmodium falciparum cGMP-dependent Protein Kinase Reveal a Novel Capping Triad Crucial for Merozoite Egress. Plos Pathog., 11, 2015

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