5JIX

PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-Br-cGMP

Summary for 5JIX

• Entry DOI: 10.2210/pdb5jix/pdb
• Related: 5JIZ
• Descriptor: cGMP-dependent protein kinase 2, CALCIUM ION, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: cyclic gmp-dependent protein kinase type ii, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Apical cell membrane ; Lipid-anchor : Q13237
• Total number of polymer chains: 1
• Total formula weight: 18710.61

Authors

Campbell, J.C.,Kim, C.W. (deposition date: 2016-04-22, release date: 2017-05-03, Last modification date: 2023-09-27)

• Primary citation: Campbell, J.C.,Henning, P.,Franz, E.,Sankaran, B.,Herberg, F.W.,Kim, C.; Structural Basis of Analog Specificity in PKG I and II.; ACS Chem. Biol., 12:2388-2398, 2017; PubMed: 28793191; DOI: 10.1021/acschembio.7b00369

Experimental method

X-RAY DIFFRACTION (1.47 Å)