5JIX
PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-Br-cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cGMP-dependent protein kinase 2 | polymer | 152 | 17394.4 | 1 | UniProt (Q13237) Pfam (PF00027) | Homo sapiens (Human) | cGK2,cGMP-dependent protein kinase II,cGKII |
| 2 | B, C, D, E (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | F, G, H, I, J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | K (A) | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL | non-polymer | 398.5 | 1 | Chemie (PE5) | |||
| 5 | L (A) | 2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-1,9-dihydro-6H-purin-6-one | non-polymer | 424.1 | 1 | Chemie (6J7) | |||
| 6 | M (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | N (A) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A: 269 - 418 (UniProt: Q13237)
| PDB | External Database | Details |
|---|---|---|
| Gly 267 | - | expression tag |
| Ser 268 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17394.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1316.2 | |
| All* | Total formula weight | 18710.6 |
