5JIX
PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-Br-cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cGMP-dependent protein kinase 2 | polymer | 152 | 17394.4 | 1 | UniProt (Q13237) Pfam (PF00027) | Homo sapiens (Human) | cGK2,cGMP-dependent protein kinase II,cGKII |
| 2 | B, C, D, E (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) PubChem (271) | |||
| 3 | F, G, H, I, J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | K (A) | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL | non-polymer | 398.5 | 1 | Chemie (PE5) PubChem (657096) | |||
| 5 | L (A) | 2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-1,9-dihydro-6H-purin-6-one | non-polymer | 424.1 | 1 | Chemie (6J7) PubChem (135419186) PubChem (135494411) PubChem (135484643) PubChem (135484657) PubChem (135510968) PubChem (135526720) PubChem (135665278) PubChem (135873471) PubChem (136183230) PubChem (136183236) PubChem (136454904) PubChem (136454907) PubChem (136488080) PubChem (136488087) PubChem (136611828) PubChem (137138804) PubChem (137140602) | |||
| 6 | M (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 7 | N (A) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A: 269 - 418 (UniProt: Q13237)
| PDB | External Database | Details |
|---|---|---|
| Gly 267 | - | expression tag |
| Ser 268 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17394.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1316.2 | |
| All* | Total formula weight | 18710.6 |
