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1BY3
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FHUA FROM E. COLI
Descriptor: N-OCTYL-2-HYDROXYETHYL SULFOXIDE, PROTEIN (FERRICHROME-IRON RECEPTOR PRECURSOR (FHUA))
Authors:Locher, K.P, Rees, B, Koebnik, R, Mitschler, A, Moulinier, L, Rosenbusch, J.P, Moras, D.
Deposit date:1998-10-22
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes.
Cell(Cambridge,Mass.), 95, 1998
1BMN
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HUMAN ALPHA-THROMBIN COMPLEXED WITH [S-(R*,R*)]-1-(AMINOIMINOMETHYL)-N-[[1-[N-[(2-NAPHTHALENYLSULFONYL)-L-SERYL]-PYRROLIDINYL]METHYL]-3-PIPERIDENECARBOXAMIDE (BMS-189090)
Descriptor: ALPHA-THROMBIN, HIRUDIN I, [S-(R*,R*)]-1-(AMINOIMINOMETHYL)-N-[[1-[N-[(2-NAPHTHALENYLSULFONYL)-L-SERYL]-3-PYRROLIDINYL]METHYL]-3-PIPERIDENECARBOXA MIDE
Authors:Malley, M, Sack, J.
Deposit date:1995-11-14
Release date:1996-12-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090.
Protein Sci., 5, 1996
1BPJ
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THYMIDYLATE SYNTHASE R178T, R179T DOUBLE MUTANT
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, POTASSIUM ION, PROTEIN (THYMIDYLATE SYNTHASE)
Authors:Morse, R.J, Finer-Moore, J.S, Stroud, R.M.
Deposit date:1998-08-11
Release date:1998-08-19
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Energetic contributions of four arginines to phosphate-binding in thymidylate synthase are more than additive and depend on optimization of "effective charge balance".
Biochemistry, 39, 2000
1C1Q
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RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES
Descriptor: (5-AMIDINO-2-BENZIMIDAZOLYL)(2-BENZIMIDAZOLYL)METHANE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Katz, B.A, Luong, C.
Deposit date:1999-07-21
Release date:2000-07-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1C3X
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PURINE NUCLEOSIDE PHOSPHORYLASE FROM CELLULOMONAS SP. IN COMPLEX WITH 8-IODO-GUANINE
Descriptor: 8-IODO-GUANINE, CALCIUM ION, PENTOSYLTRANSFERASE, ...
Authors:Tebbe, J, Bzowska, A, Wielgus-Kutrowska, B, Schroeder, W, Kazimierczuk, Z, Shugar, D, Saenger, W, Koellner, G.
Deposit date:1999-07-29
Release date:1999-12-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
J.Mol.Biol., 294, 1999
1BJ3
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CRYSTAL STRUCTURE OF COAGULATION FACTOR IX-BINDING PROTEIN (IX-BP) FROM VENOM OF HABU SNAKE WITH A HETERODIMER OF C-TYPE LECTIN DOMAINS
Descriptor: CALCIUM ION, PROTEIN (COAGULATION FACTOR IX-BINDING PROTEIN A), PROTEIN (COAGULATION FACTOR IX-BINDING PROTEIN B)
Authors:Mizuno, H, Fujimoto, Z, Koizumi, M, Kano, H, Atoda, H, Morita, T.
Deposit date:1998-07-02
Release date:1999-08-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of coagulation factor IX-binding protein from habu snake venom at 2.6 A: implication of central loop swapping based on deletion in the linker region.
J.Mol.Biol., 289, 1999
1BXC
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XYLOSE ISOMERASE FROM THERMUS CALDOPHILUS
Descriptor: XYLOSE ISOMERASE
Authors:Chang, C, Park, B.C, Lee, D.-S, Suh, S.W.
Deposit date:1998-10-02
Release date:1999-02-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of thermostable xylose isomerases from Thermus caldophilus and Thermus thermophilus: possible structural determinants of thermostability.
J.Mol.Biol., 288, 1999
1BT4
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PHOSPHOSERINE AMINOTRANSFERASE FROM BACILLUS CIRCULANS SUBSP. ALKALOPHILUS
Descriptor: PYRIDOXAL-5'-PHOSPHATE, Phosphoserine aminotransferase
Authors:Hester, G, Luong, T.N, Moser, M, Jansonius, J.N.
Deposit date:1998-09-02
Release date:1998-09-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of Phosphoserine Aminotransferase from Bacillus Circulans Subsp. Alkalophilus
To be Published
1BU1
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BU of 1bu1 by Molmil
SRC FAMILY KINASE HCK SH3 DOMAIN
Descriptor: PROTEIN (HEMOPOIETIC CELL KINASE)
Authors:Arold, S, Franken, P, Dumas, C.
Deposit date:1998-09-09
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.
Biochemistry, 37, 1998
1BLN
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ANTI-P-GLYCOPROTEIN FAB MRK-16
Descriptor: PROTEIN (MONOCLONAL ANTIBODY MRK-16 (HEAVY CHAIN)), PROTEIN (MONOCLONAL ANTIBODY MRK-16 (LIGHT CHAIN))
Authors:Vasudevan, S, Tsuruo, T, Rose, D.R.
Deposit date:1998-07-16
Release date:1998-10-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mode of binding of anti-P-glycoprotein antibody MRK-16 to its antigen. A crystallographic and molecular modeling study.
J.Biol.Chem., 273, 1998
1MXO
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AmpC beta-lactamase in complex with an m.carboxyphenylglycylboronic acid bearing the cephalothin R1 side chain
Descriptor: (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION
Authors:Morandi, F, Caselli, E, Morandi, S, Focia, P.J, Blazquez, J, Shoichet, B.K, Prati, F.
Deposit date:2002-10-02
Release date:2003-03-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Nanomolar inhibitors of AmpC beta-lactamase.
J.Am.Chem.Soc., 125, 2003
1BMB
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BU of 1bmb by Molmil
GRB2-SH2 DOMAIN IN COMPLEX WITH KPFY*VNVEF (PKF270-974)
Descriptor: PROTEIN (GROWTH FACTOR RECEPTOR BOUND PROTEIN 2), PROTEIN (PKF270-974)
Authors:Rondeau, J.M, Zurini, M.
Deposit date:1998-07-23
Release date:1998-07-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1).
J.Med.Chem., 42, 1999
1BT3
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CATECHOL OXIDASE FROM IPOMOEA BATATAS (SWEET POTATOES) IN THE NATIVE CU(II)-CU(II) STATE
Descriptor: CU-O-CU LINKAGE, PROTEIN (CATECHOL OXIDASE)
Authors:Klabunde, T, Eicken, C, Sacchettini, J.C, Krebs, B.
Deposit date:1998-09-02
Release date:1999-09-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a plant catechol oxidase containing a dicopper center.
Nat.Struct.Biol., 5, 1998
1BTH
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STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR
Descriptor: BOVINE PANCREATIC TRYPSIN INHIBITOR, THROMBIN
Authors:Van De Locht, A, Bode, W, Stubbs, M.T.
Deposit date:1996-12-03
Release date:1997-12-24
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin.
EMBO J., 16, 1997
1BUD
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BU of 1bud by Molmil
ACUTOLYSIN A FROM SNAKE VENOM OF AGKISTRODON ACUTUS AT PH 5.0
Descriptor: CALCIUM ION, PROTEIN (ACUTOLYSIN A), ZINC ION
Authors:Gong, W, Zhu, X, Liu, S, Teng, M, Niu, L.
Deposit date:1998-09-03
Release date:1999-09-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus.
J.Mol.Biol., 283, 1998
1BX0
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Ferredoxin:nadp+ oxidoreductase (ferredoxin reductase) mutant e312l
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, PROTEIN (FERREDOXIN:NADP+ OXIDOREDUCTASE), ...
Authors:Aliverti, A, Deng, Z, Ravasi, D, Piubelli, L, Karplus, P.A, Zanetti, G.
Deposit date:1998-10-10
Release date:1998-10-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase.
J.Biol.Chem., 273, 1998
1BXA
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AMICYANIN REDUCED, PH 4.4, 1.3 ANGSTROMS
Descriptor: COPPER (I) ION, PROTEIN (AMICYANIN)
Authors:Cunane, L.M, Chen, Z.W, Durley, R.C.E, Mathews, F.S.
Deposit date:1998-10-01
Release date:1998-10-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Molecular basis for interprotein complex-dependent effects on the redox properties of amicyanin.
Biochemistry, 37, 1998
1BWU
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BU of 1bwu by Molmil
MANNOSE-SPECIFIC AGGLUTININ (LECTIN) FROM GARLIC (ALLIUM SATIVUM) BULBS COMPLEXED WITH ALPHA-D-MANNOSE
Descriptor: PROTEIN (AGGLUTININ), alpha-D-mannopyranose
Authors:Chandra, N.R, Ramachandraiah, G, Bachhawat, K, Dam, T.K, Surolia, A, Vijayan, M.
Deposit date:1998-09-28
Release date:1999-01-20
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a dimeric mannose-specific agglutinin from garlic: quaternary association and carbohydrate specificity.
J.Mol.Biol., 285, 1999
1BXE
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RIBOSOMAL PROTEIN L22 FROM THERMUS THERMOPHILUS
Descriptor: CHLORIDE ION, PROTEIN (RIBOSOMAL PROTEIN L22)
Authors:Unge, J, Aberg, A, Al-Karadaghi, S, Nikulin, A, Nikonov, S, Davydova, N, Nevskaya, N, Garber, M, Liljas, A.
Deposit date:1998-10-02
Release date:1998-10-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance.
Structure, 6, 1998
1BXS
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BU of 1bxs by Molmil
SHEEP LIVER CLASS 1 ALDEHYDE DEHYDROGENASE WITH NAD BOUND
Descriptor: ALDEHYDE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Moore, S.A, Baker, H.M, Blythe, T.J, Kitson, K.E, Kitson, T.M, Baker, E.N.
Deposit date:1998-10-08
Release date:1999-04-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases.
Structure, 6, 1998
1BYL
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BLEOMYCIN RESISTANCE PROTEIN FROM STREPTOALLOTEICHUS HINDUSTANUS
Descriptor: PROTEIN (BLEOMYCIN RESISTANCE PROTEIN)
Authors:Dumas, P, Bergdoll, M, Cagnon, C, Masson, J.M.
Deposit date:1998-10-17
Release date:1999-10-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and site-directed mutagenesis of a bleomycin resistance protein and their significance for drug sequestering.
EMBO J., 13, 1994
1BYS
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CRYSTAL STRUCTURE OF NUC COMPLEXED WITH TUNGSTATE
Descriptor: PROTEIN (ENDONUCLEASE), TUNGSTATE(VI)ION
Authors:Stuckey, J.A, Dixon, J.E.
Deposit date:1998-10-19
Release date:1999-10-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a phospholipase D family member.
Nat.Struct.Biol., 6, 1999
1BXH
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CONCANAVALIN A COMPLEXED TO METHYL ALPHA1-2 MANNOBIOSIDE
Descriptor: CALCIUM ION, Concanavalin-A, MANGANESE (II) ION, ...
Authors:Moothoo, D.N, Canaan, B, Field, R.A, Naismith, J.H.
Deposit date:1998-10-02
Release date:1998-10-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Man alpha1-2 Man alpha-OMe-concanavalin A complex reveals a balance of forces involved in carbohydrate recognition.
Glycobiology, 9, 1999
1BNT
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CARBONIC ANHYDRASE II INHIBITOR
Descriptor: 3,4-DIHYDRO-4-HYDROXY-2-(4-METHOXYPHENYL)-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, CARBONIC ANHYDRASE, MERCURY (II) ION, ...
Authors:Boriack-Sjodin, P.A, Zeitlin, S, Christianson, D.W.
Deposit date:1998-07-30
Release date:1999-06-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural analysis of inhibitor binding to human carbonic anhydrase II.
Protein Sci., 7, 1998
1BIX
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THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES
Descriptor: AP ENDONUCLEASE 1, PLATINUM (II) ION, SAMARIUM (III) ION
Authors:Gorman, M.A, Morera, S, Rothwell, D.G, De La Fortelle, E, Mol, C.D, Tainer, J.A, Hickson, I.D, Freemont, P.S.
Deposit date:1998-06-19
Release date:1999-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
EMBO J., 16, 1997

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