1BIX

THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES

Summary for 1BIX

DescriptorAP ENDONUCLEASE 1, SAMARIUM (III) ION, PLATINUM (II) ION, ... (4 entities in total)
Functional Keywordsdna repair, endonuclease, hap1, ref-1, abasic site recognition
Biological sourceHomo sapiens (human)
Cellular locationNucleus. DNA-(apurinic or apyrimidinic site) lyase, mitochondrial: Mitochondrion P27695
Total number of polymer chains1
Total molecular weight33084.2
Authors
Gorman, M.A.,Morera, S.,Rothwell, D.G.,De La Fortelle, E.,Mol, C.D.,Tainer, J.A.,Hickson, I.D.,Freemont, P.S. (deposition date: 1998-06-19, release date: 1999-06-22, Last modification date: 2011-07-13)
Primary citation
Gorman, M.A.,Morera, S.,Rothwell, D.G.,de La Fortelle, E.,Mol, C.D.,Tainer, J.A.,Hickson, I.D.,Freemont, P.S.
The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
EMBO J., 16:6548-6558, 1997
PubMed: 9351835 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/16.21.6548
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers50.7%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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