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1BMB

GRB2-SH2 DOMAIN IN COMPLEX WITH KPFY*VNVEF (PKF270-974)

Summary for 1BMB
Entry DOI10.2210/pdb1bmb/pdb
DescriptorPROTEIN (GROWTH FACTOR RECEPTOR BOUND PROTEIN 2), PROTEIN (PKF270-974) (3 entities in total)
Functional Keywordssh2 domain, signal transduction, adaptor protein, ras pathway, hormone-growth factor complex, hormone/growth factor
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight15569.53
Authors
Rondeau, J.M.,Zurini, M. (deposition date: 1998-07-23, release date: 1998-07-29, Last modification date: 2023-11-15)
Primary citationEttmayer, P.,France, D.,Gounarides, J.,Jarosinski, M.,Martin, M.S.,Rondeau, J.M.,Sabio, M.,Topiol, S.,Weidmann, B.,Zurini, M.,Bair, K.W.
Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1).
J.Med.Chem., 42:971-980, 1999
Cited by
PubMed: 10090780
DOI: 10.1021/jm9811007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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