4PIG
| Crystal structure of the ubiquitin K11S mutant | Descriptor: | CALCIUM ION, CHLORIDE ION, SODIUM ION, ... | Authors: | Loll, P.J, Xu, P.J, Schmidt, J, Melideo, S.L. | Deposit date: | 2014-05-08 | Release date: | 2014-10-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.952 Å) | Cite: | Enhancing ubiquitin crystallization through surface-entropy reduction. Acta Crystallogr.,Sect.F, 70, 2014
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2MRF
| NMR structure of the ubiquitin-binding zinc finger (UBZ) domain from human Rad18 | Descriptor: | E3 ubiquitin-protein ligase RAD18, ZINC ION | Authors: | Rizzo, A.A, Salerno, P.E, Bezsonova, I, Korzhnev, D.M. | Deposit date: | 2014-07-03 | Release date: | 2014-10-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response. Biochemistry, 53, 2014
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2GBN
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2M0X
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2HLW
| Solution Structure of the Human Ubiquitin-conjugating Enzyme Variant Uev1a | Descriptor: | Ubiquitin-conjugating enzyme E2 variant 1 | Authors: | Hau, D.D, Lewis, M.J, Saltibus, L.F, Pastushok, L, Xiao, W, Spyracopoulos, L. | Deposit date: | 2006-07-10 | Release date: | 2006-09-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure and interactions of the ubiquitin-conjugating enzyme variant human uev1a: implications for enzymatic synthesis of polyubiquitin chains(,). Biochemistry, 45, 2006
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4JUE
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2F4W
| Human ubiquitin-conjugating enzyme E2 J2 | Descriptor: | ubiquitin-conjugating enzyme E2, J2 | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Finerty Jr, P.J, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2005-11-24 | Release date: | 2005-12-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
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2OB4
| Human Ubiquitin-Conjugating Enzyme CDC34 | Descriptor: | Ubiquitin-conjugating enzyme E2-32 kDa complementing | Authors: | Neculai, D, Avvakumov, G.V, Xue, S, Walker, J.R, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Sicheri, F, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2006-12-18 | Release date: | 2006-12-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
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2KR1
| Solution NMR structure of zinc binding N-terminal domain of ubiquitin-protein ligase E3A from Homo Sapiens. Northeast Structural Genomics Consortium (NESG) target HR3662 | Descriptor: | Ubiquitin protein ligase E3A, ZINC ION | Authors: | Lemak, A, Yee, A, Fares, C, Semesi, A, Xiao, R, Montelione, G, Dhe-Paganon, S, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-27 | Release date: | 2009-12-22 | Last modified: | 2020-02-26 | Method: | SOLUTION NMR | Cite: | Zn-binding AZUL domain of human ubiquitin protein ligase Ube3A. J.Biomol.Nmr, 51, 2011
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3BZH
| Crystal structure of human ubiquitin-conjugating enzyme E2 E1 | Descriptor: | GLYCEROL, Ubiquitin-conjugating enzyme E2 E1 | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-01-18 | Release date: | 2008-02-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
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2QHO
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2QIZ
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2GBR
| Crystal Structure of the 35-36 MoaD Insertion Mutant of Ubiquitin | Descriptor: | CADMIUM ION, Ubiquitin | Authors: | Ferraro, D.M, Ferraro, D.J, Ramaswamy, S, Robertson, A.D. | Deposit date: | 2006-03-10 | Release date: | 2006-05-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Ubiquitin Insertion Mutants Support Site-specific Reflex Response to Insertions Hypothesis. J.Mol.Biol., 359, 2006
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7OD1
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4FJV
| Crystal Structure of Human Otubain2 and Ubiquitin Complex | Descriptor: | ETHANAMINE, GLYCEROL, Polyubiquitin-C, ... | Authors: | Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M. | Deposit date: | 2012-06-12 | Release date: | 2013-06-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages. Plos One, 10, 2015
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5OXI
| C-terminally retracted ubiquitin L67S mutant | Descriptor: | SULFATE ION, Ubiquitin L67S mutant | Authors: | Gladkova, C.G, Schubert, A.F, Wagstaff, J.L, Pruneda, J.N, Freund, S.M.V, Komander, D. | Deposit date: | 2017-09-06 | Release date: | 2017-11-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1. EMBO J., 36, 2017
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5OXH
| C-terminally retracted ubiquitin T66V/L67N mutant | Descriptor: | SULFATE ION, Ubiquitin T66V/L67N mutant | Authors: | Gladkova, C, Schubert, A.F, Wagstaff, J.L, Pruneda, J.P, Freund, S.M.V, Komander, D. | Deposit date: | 2017-09-06 | Release date: | 2017-11-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1. EMBO J., 36, 2017
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4XKL
| Crystal structure of NDP52 ZF2 in complex with mono-ubiquitin | Descriptor: | ACETATE ION, Calcium-binding and coiled-coil domain-containing protein 2, GLYCEROL, ... | Authors: | Xie, X, Li, F, Wang, Y, Lin, Z, Chen, X, Liu, J, Pan, L. | Deposit date: | 2015-01-12 | Release date: | 2015-11-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis of ubiquitin recognition by the autophagy receptor CALCOCO2 Autophagy, 11, 2015
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1W6V
| Solution structure of the DUSP domain of hUSP15 | Descriptor: | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 | Authors: | De Jong, R.D, Ab, E, Diercks, T, Truffault, V, Daniels, M, Kaptein, R, Folkers, G.E. | Deposit date: | 2004-08-24 | Release date: | 2006-01-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Human Ubiquitin-Specific Protease 15 Dusp Domain. J.Biol.Chem., 281, 2006
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7Z8B
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7ZF1
| Structure of ubiquitinated FANCI in complex with FANCD2 and double-stranded DNA | Descriptor: | DNA (61-MER), Fanconi anemia group D2 protein, Fanconi anemia group I protein, ... | Authors: | Lemonidis, K, Rennie, M.L, Arkinson, C, Streetley, J, Clarke, M, Chaugule, V.K, Walden, H. | Deposit date: | 2022-03-31 | Release date: | 2022-11-16 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.14 Å) | Cite: | Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination. Embo J., 42, 2023
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4WHV
| E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B | Descriptor: | E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ... | Authors: | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | Deposit date: | 2014-09-23 | Release date: | 2015-09-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (8.3 Å) | Cite: | RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment. J.Biol.Chem., 291, 2016
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6DXH
| Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-tert-butylphenyl)-4-oxobutanoate | Descriptor: | 4-(4-tert-butylphenyl)-4-oxobutanoic acid, UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 5, ... | Authors: | Harding, R.J, Mann, M.K, Ravichandran, M, Ferreira de Freitas, R, Franzoni, I, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Schapira, M, Structural Genomics Consortium (SGC) | Deposit date: | 2018-06-28 | Release date: | 2018-07-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain. J.Med.Chem., 62, 2019
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6DXT
| Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoate | Descriptor: | 1,2-ETHANEDIOL, 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoic acid, UNKNOWN ATOM OR ION, ... | Authors: | Mann, M.K, Harding, R.J, Ravichandran, M, Ferreira de Freitas, R, Franzoni, I, Bountra, C, Edwards, A.M, Arrowsmith, C.M, Schapira, M, Structural Genomics Consortium (SGC) | Deposit date: | 2018-06-29 | Release date: | 2018-08-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain. J.Med.Chem., 62, 2019
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4WPH
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