Crystal structure of the UBA domain from EDD ubiquitin ligase in complex with ubiquitin

Summary for 2QHO

DescriptorUbiquitin, E3 ubiquitin-protein ligase EDD1 (3 entities in total)
Functional Keywordsprotein-protein complex, protein binding-ligase complex, protein binding/ligase
Biological sourceHomo sapiens (human)
Cellular locationNucleus O95071
Total number of polymer chains8
Total molecular weight57585.4
Kozlov, G.,Gehring, K. (deposition date: 2007-07-02, release date: 2007-09-25, Last modification date: 2011-07-13)
Primary citation
Kozlov, G.,Nguyen, L.,Lin, T.,De Crescenzo, G.,Park, M.,Gehring, K.
Structural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDD.
J.Biol.Chem., 282:35787-35795, 2007
PubMed: 17897937 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M705655200
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.256604.7%0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report