7Z8B

Structure of CRL7FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation

Summary for 7Z8B

Entry DOI	10.2210/pdb7z8b/pdb
EMDB information	14547
Descriptor	Cullin-7, F-box/WD repeat-containing protein 8, E3 ubiquitin-protein ligase RBX1, ... (5 entities in total)
Functional Keywords	cullin-ring ubiquitin e3 ligase, ligase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	290359.38
Authors	Hopf, L.V.M.,Schulman, B.A. (deposition date: 2022-03-17, release date: 2022-08-24, Last modification date: 2024-07-24)
Primary citation	Hopf, L.V.M.,Baek, K.,Klugel, M.,von Gronau, S.,Xiong, Y.,Schulman, B.A. Structure of CRL7 FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation. Nat.Struct.Mol.Biol., 29:854-862, 2022 Cited by PubMed: 35982156 DOI: 10.1038/s41594-022-00815-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation