2F4W

Human ubiquitin-conjugating enzyme E2 J2

Summary for 2F4W

Descriptorubiquitin-conjugating enzyme E2, J2 (2 entities in total)
Functional Keywordsendoplasmic reticulum, ligase, ubl conjugation pathway, structural genomics consortium (sgc)
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight42665.05
Authors
Primary citation
Sheng, Y.,Hong, J.H.,Doherty, R.,Srikumar, T.,Shloush, J.,Avvakumov, G.V.,Walker, J.R.,Xue, S.,Neculai, D.,Wan, J.W.,Kim, S.K.,Arrowsmith, C.H.,Raught, B.,Dhe-Paganon, S.
A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11:329-341, 2012
PubMed: 22496338 (PDB entries with the same primary citation)
DOI: 10.1074/mcp.O111.013706
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.250904.4%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2f4w
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Molmil generated image of 2f4w
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Molmil generated image of 2f4w
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More Biological unit images

Molmil generated image of 2f4w
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Molmil generated image of 2f4w
rotated about x axis by 90°
Molmil generated image of 2f4w
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2f4w.pdb1.gz [27.88 KB])
Coordinate files for Biological unit (2f4w.pdb2.gz [29.48 KB])