2F4W
Human ubiquitin-conjugating enzyme E2 J2
Summary for 2F4W
Entry DOI | 10.2210/pdb2f4w/pdb |
Descriptor | ubiquitin-conjugating enzyme E2, J2 (2 entities in total) |
Functional Keywords | endoplasmic reticulum, ligase, ubl conjugation pathway, structural genomics consortium (sgc) |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 42665.05 |
Authors | Walker, J.R.,Avvakumov, G.V.,Xue, S.,Finerty Jr., P.J.,Newman, E.M.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2005-11-24, release date: 2005-12-27, Last modification date: 2023-08-23) |
Primary citation | Sheng, Y.,Hong, J.H.,Doherty, R.,Srikumar, T.,Shloush, J.,Avvakumov, G.V.,Walker, J.R.,Xue, S.,Neculai, D.,Wan, J.W.,Kim, S.K.,Arrowsmith, C.H.,Raught, B.,Dhe-Paganon, S. A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11:329-341, 2012 Cited by PubMed: 22496338DOI: 10.1074/mcp.O111.013706 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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