7OD1

Crystal structure of RBR ubiquitin ligase ARIH2

Summary for 7OD1

Entry DOI	10.2210/pdb7od1/pdb
Descriptor	E3 ubiquitin-protein ligase ARIH2, ZINC ION (3 entities in total)
Functional Keywords	triad1, arih2, rbr, ubiquitin, e3 ligase, ligase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	116572.60
Authors	Kostrhon, S.P.,Prabu, J.R.,Schulman, B.A. (deposition date: 2021-04-28, release date: 2021-09-15, Last modification date: 2021-10-06)
Primary citation	Kostrhon, S.,Prabu, J.R.,Baek, K.,Horn-Ghetko, D.,von Gronau, S.,Klugel, M.,Basquin, J.,Alpi, A.F.,Schulman, B.A. CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation. Nat.Chem.Biol., 17:1075-1083, 2021 Cited by PubMed: 34518685 DOI: 10.1038/s41589-021-00858-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation