7O52
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![BU of 7o52 by Molmil](/molmil-images/mine/7o52) | CD22 d6-d7 in complex with Fab m971 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD22 d6-d7 Ig domains, GLYCEROL, ... | Authors: | Ereno-Orbea, J, Sicard, T, Julien, J.P. | Deposit date: | 2021-04-07 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22. J.Biol.Chem., 297, 2021
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7QF1
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![BU of 7qf1 by Molmil](/molmil-images/mine/7qf1) | Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.6264 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CV2.6264 heavy chain, CV2.6264 light chain, ... | Authors: | Fernandez, I, Pederzoli, R, Rey, F.A. | Deposit date: | 2021-12-03 | Release date: | 2022-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
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7QF0
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![BU of 7qf0 by Molmil](/molmil-images/mine/7qf0) | Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.2325 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CV2.2325 heavy chain, ... | Authors: | Fernandez, I, Pederzoli, R, Rey, F.A. | Deposit date: | 2021-12-03 | Release date: | 2022-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
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6V9U
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![BU of 6v9u by Molmil](/molmil-images/mine/6v9u) | Crystal structure of human TLR8 ectodomain bound to small molecule antagonist 14c | Descriptor: | 2-(3,4-dimethoxyphenyl)-5-(piperidin-4-yl)-3-(propan-2-yl)-1H-indole, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Critton, D.A. | Deposit date: | 2019-12-16 | Release date: | 2020-08-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9). Acs Med.Chem.Lett., 11, 2020
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1G1T
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![BU of 1g1t by Molmil](/molmil-images/mine/1g1t) | CRYSTAL STRUCTURE OF E-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH SLEX | Descriptor: | CALCIUM ION, E-SELECTIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside | Authors: | Somers, W.S, Camphausen, R.T. | Deposit date: | 2000-10-13 | Release date: | 2001-10-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1. Cell(Cambridge,Mass.), 103, 2000
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7TCT
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![BU of 7tct by Molmil](/molmil-images/mine/7tct) | Integrin alaphIIBbeta3 complex with UR2922 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Zhu, J, Lin, F.-Y, Zhu, J, Springer, T.A. | Deposit date: | 2021-12-28 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7ANQ
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![BU of 7anq by Molmil](/molmil-images/mine/7anq) | Complete PCSK9 C-ter domain in complex with VHH P1.40 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Proprotein convertase subtilisin/kexin type 9, SULFATE ION, ... | Authors: | Ciccone, L, Legrand, P, Stura, E.A, Dive, V, Seidahn, N.G, Fruchart Gaillard, C. | Deposit date: | 2020-10-12 | Release date: | 2021-10-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels. Mol Metab, 67, 2022
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8UT2
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![BU of 8ut2 by Molmil](/molmil-images/mine/8ut2) | Pre-fusion Measles virus fusion protein complexed with Fab 77 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zyla, D, Saphire, E.O. | Deposit date: | 2023-10-30 | Release date: | 2024-07-03 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | A neutralizing antibody prevents postfusion transition of measles virus fusion protein. Science, 384, 2024
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8UUQ
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![BU of 8uuq by Molmil](/molmil-images/mine/8uuq) | |
8FYY
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![BU of 8fyy by Molmil](/molmil-images/mine/8fyy) | |
6SGV
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![BU of 6sgv by Molmil](/molmil-images/mine/6sgv) | Crystal structure of AcAChBP in complex with hosieine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Hosieine, ... | Authors: | Hunter, W.N, Dawson, A, Parker, H. | Deposit date: | 2019-08-05 | Release date: | 2020-08-26 | Last modified: | 2022-09-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Delineating the activity of the potent nicotinic acetylcholine receptor agonists (+)-anatoxin-a and (-)-hosieine-A Acta Crystallogr.,Sect.F, 2022
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6F5K
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![BU of 6f5k by Molmil](/molmil-images/mine/6f5k) | Crystal structure of laccase from Myceliophthora thermophila | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Ernst, H.A, Joergensen, L.J, Piontek, K, Bukh, C, Oestergaard, L.H, Larsen, S, Bjerrum, M.J. | Deposit date: | 2017-12-01 | Release date: | 2018-12-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | A comparative structural analysis of the surface properties of asco-laccases. Plos One, 13, 2018
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8GX9
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6V1C
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![BU of 6v1c by Molmil](/molmil-images/mine/6v1c) | Crystal structure of human trefoil factor 3 in complex with its cognate ligand | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-galactopyranose, Trefoil factor 3 | Authors: | Jarva, M.A, Lingford, J.P, John, A, Scott, N.E, Goddard-Borger, E.D. | Deposit date: | 2019-11-20 | Release date: | 2019-12-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Trefoil factors share a lectin activity that defines their role in mucus. Nat Commun, 11, 2020
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6STT
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![BU of 6stt by Molmil](/molmil-images/mine/6stt) | Adenovirus 29 Fiber Knob protein in complex with Sialic acid | Descriptor: | Fiber, N-acetyl-alpha-neuraminic acid | Authors: | Baker, A.T, Mundy, R.M, Rizkallah, P.J, Parker, A.L. | Deposit date: | 2019-09-11 | Release date: | 2021-03-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Broad sialic acid usage amongst species D human adenovirus npj Viruses, 1, 2023
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7QQB
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![BU of 7qqb by Molmil](/molmil-images/mine/7qqb) | Crystal structure of the envelope glycoprotein complex of Puumala virus in complex with the scFv fragment of the broadly neutralizing human antibody ADI-42898 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, GLYCEROL, ... | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | Deposit date: | 2022-01-07 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody. Sci Transl Med, 15, 2023
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8QJ0
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![BU of 8qj0 by Molmil](/molmil-images/mine/8qj0) | Room-temperature Serial Synchrotron Crystallography structure of Spinacia oleracea RuBisCO | Descriptor: | MAGNESIUM ION, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small subunit, ... | Authors: | Bjelcic, M, Neutze, R, Aurelius, O, Nan, J, Ursby, T. | Deposit date: | 2023-09-12 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Room-temperature serial synchrotron crystallography structure of Spinacia oleracea RuBisCO. Acta Crystallogr.,Sect.F, 80, 2024
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6VLD
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![BU of 6vld by Molmil](/molmil-images/mine/6vld) | Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 bound to GDP and A2SGP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARAGINE, Alpha-(1,6)-fucosyltransferase, ... | Authors: | Jarva, M.A, Dramicanin, M, Lingford, J.P, Mao, R, John, A, Goddard-Borger, E.D. | Deposit date: | 2020-01-23 | Release date: | 2020-02-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural basis of substrate recognition and catalysis by fucosyltransferase 8. J.Biol.Chem., 295, 2020
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6SU0
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![BU of 6su0 by Molmil](/molmil-images/mine/6su0) | Crystal structure of dimethylated RSLex in complex with cucurbit[7]uril | Descriptor: | Fucose-binding lectin protein, SODIUM ION, cucurbit[7]uril, ... | Authors: | Guagnini, F, Engilberge, S, Crowley, P.B. | Deposit date: | 2019-09-12 | Release date: | 2020-02-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Engineered assembly of a protein-cucurbituril biohybrid. Chem.Commun.(Camb.), 56, 2020
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8RML
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![BU of 8rml by Molmil](/molmil-images/mine/8rml) | |
8RMM
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![BU of 8rmm by Molmil](/molmil-images/mine/8rmm) | |
7OZ5
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![BU of 7oz5 by Molmil](/molmil-images/mine/7oz5) | Crystal structure of HIV-1 reverse transcriptase with a double stranded DNA in complex with fragment 166 at the transient P-pocket. | Descriptor: | (1~{R},2~{R})-2-phenyl-~{N}-(1,3-thiazol-2-yl)cyclopropane-1-carboxamide, CADMIUM ION, DNA (28-MER), ... | Authors: | Martinez, S.E, Singh, A.K, Das, K. | Deposit date: | 2021-06-25 | Release date: | 2021-12-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.37 Å) | Cite: | Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening. Nat Commun, 12, 2021
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7QZU
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![BU of 7qzu by Molmil](/molmil-images/mine/7qzu) | Structure of liver pyruvate kinase in complex with anthraquinone derivative 47 | Descriptor: | (2~{S})-2-[2-[4-[3,4-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen-2-yl]sulfonylpiperazin-1-yl]-2-oxidanylidene-ethyl]-2-oxidanyl-butanedioic acid, 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, ... | Authors: | Lulla, A, Foller, A, Nain-Perez, A, Grotli, M, Brear, P, Hyvonen, M. | Deposit date: | 2022-01-31 | Release date: | 2022-04-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.964 Å) | Cite: | Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase. Eur.J.Med.Chem., 234, 2022
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7RPY
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![BU of 7rpy by Molmil](/molmil-images/mine/7rpy) | X25-2 domain of Sca5 from Ruminococcus bromii | Descriptor: | ACETATE ION, Cohesin-containing protein, GLYCEROL, ... | Authors: | Cerqueira, F, Koropatkin, N. | Deposit date: | 2021-08-04 | Release date: | 2022-04-13 | Last modified: | 2022-05-25 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Sas20 is a highly flexible starch-binding protein in the Ruminococcus bromii cell-surface amylosome. J.Biol.Chem., 298, 2022
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8RMK
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![BU of 8rmk by Molmil](/molmil-images/mine/8rmk) | |