8UT2

Pre-fusion Measles virus fusion protein complexed with Fab 77

Summary for 8UT2

Entry DOI	10.2210/pdb8ut2/pdb
EMDB information	42527
Descriptor	Fusion glycoprotein F0, mAb 77 Light chain, mAb 77 Heavy Chain, ... (7 entities in total)
Functional Keywords	viral protein, glycoprotein, immune system, antibody, measles, high-resolution, antibody fragment, fab, neutralizing antibody, ectodomain
Biological source	Measles morbillivirus More
Total number of polymer chains	12
Total formula weight	411140.18
Authors	Zyla, D.,Saphire, E.O. (deposition date: 2023-10-30, release date: 2024-07-03, Last modification date: 2024-07-10)
Primary citation	Zyla, D.S.,Della Marca, R.,Niemeyer, G.,Zipursky, G.,Stearns, K.,Leedale, C.,Sobolik, E.B.,Callaway, H.M.,Hariharan, C.,Peng, W.,Parekh, D.,Marcink, T.C.,Diaz Avalos, R.,Horvat, B.,Mathieu, C.,Snijder, J.,Greninger, A.L.,Hastie, K.M.,Niewiesk, S.,Moscona, A.,Porotto, M.,Ollmann Saphire, E. A neutralizing antibody prevents postfusion transition of measles virus fusion protein. Science, 384:eadm8693-eadm8693, 2024 Cited by PubMed: 38935733 DOI: 10.1126/science.adm8693 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.56 Å)

Structure validation