6V1C

Crystal structure of human trefoil factor 3 in complex with its cognate ligand

Summary for 6V1C

Entry DOI	10.2210/pdb6v1c/pdb
Descriptor	Trefoil factor 3, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-galactopyranose (3 entities in total)
Functional Keywords	trefoil factor, lectin, mucin binding protein, sugar binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	7287.20
Authors	Jarva, M.A.,Lingford, J.P.,John, A.,Scott, N.E.,Goddard-Borger, E.D. (deposition date: 2019-11-20, release date: 2019-12-11, Last modification date: 2023-10-11)
Primary citation	Jarva, M.A.,Lingford, J.P.,John, A.,Soler, N.M.,Scott, N.E.,Goddard-Borger, E.D. Trefoil factors share a lectin activity that defines their role in mucus. Nat Commun, 11:2265-2265, 2020 Cited by PubMed: 32404934 DOI: 10.1038/s41467-020-16223-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation