8RML

Structure of heteromeric CALHM2/4 channel in complex with synthetic nanobody SbC4

Summary for 8RML

• Entry DOI: 10.2210/pdb8rml/pdb
• EMDB information: 19363
• Descriptor: Calcium homeostasis modulator protein 4, Synthetic nanobody SbC4, Calcium homeostasis modulator protein 2 (3 entities in total)
• Functional Keywords: ion channel, large pore channels, sybody, calhm, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 13
• Total formula weight: 430496.01

Authors

Drozdzyk, K.,Dutzler, R. (deposition date: 2024-01-08, release date: 2024-06-19)

• Primary citation: Peter, M.,Drozdzyk, K.,Dutzler, R.; Structural features of heteromeric channels composed of CALHM2 and CALHM4 paralogs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.84 Å)