8RML
Structure of heteromeric CALHM2/4 channel in complex with synthetic nanobody SbC4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, K | Calcium homeostasis modulator protein 4 | polymer | 322 | 35981.7 | 3 | UniProt (Q5JW98) Pfam (PF14798) In PDB | Homo sapiens (human) | Protein FAM26D |
2 | L, M | Synthetic nanobody SbC4 | polymer | 119 | 12877.4 | 2 | synthetic construct | ||
3 | C, D, E, F, G... | Calcium homeostasis modulator protein 2 | polymer | 331 | 37099.5 | 8 | UniProt (Q9HA72) Pfam (PF14798) In PDB | Homo sapiens (human) | Protein FAM26B |
Sequence modifications
A, B, K: 2 - 314 (UniProt: Q5JW98)
C, D, E, F, G, H, I, J: 2 - 323 (UniProt: Q9HA72)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Ser 1 | - | expression tag |
Ala 315 | - | expression tag |
Leu 316 | - | expression tag |
Glu 317 | - | expression tag |
Val 318 | - | expression tag |
Leu 319 | - | expression tag |
Phe 320 | - | expression tag |
Gln 321 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Ser 1 | - | expression tag |
Ala 324 | - | expression tag |
Leu 325 | - | expression tag |
Glu 326 | - | expression tag |
Val 327 | - | expression tag |
Leu 328 | - | expression tag |
Phe 329 | - | expression tag |
Gln 330 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 13 |
Total formula weight | 430496.0 | |
All* | Total formula weight | 430496.0 |