2ZC1
| Organophosphorus Hydrolase from Deinococcus radiodurans | Descriptor: | BROMIDE ION, COBALT (II) ION, Phosphotriesterase | Authors: | Larsen, S.D, Hawwa, R, Ratia, K, Santarsiero, B.D, Mesecar, A.D. | Deposit date: | 2007-11-02 | Release date: | 2008-11-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-Ray Structural Insights into a Phosphotriesterase to be published
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1JF7
| HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH PNU177836 | Descriptor: | 5-(2-{2-[(TERT-BUTOXY-HYDROXY-METHYL)-AMINO]-1-HYDROXY-3-PHENYL-PROPYLAMINO}-3-HYDROXY-3-PENTYLAMINO-PROPYL)-2-CARBOXYMETHOXY-BENZOIC ACID, PROTEIN-TYROSINE PHOSPHATASE 1B | Authors: | Larsen, S.D, Barf, T, Liljebris, C, May, P.D, Ogg, D, O'Sullivan, T.J, Palazuk, B.J, Schostarez, H.J, Stevens, F.C, Bleasdale, J.E. | Deposit date: | 2001-06-20 | Release date: | 2002-02-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B. J.Med.Chem., 45, 2002
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3C1U
| D192N mutant of Rhamnogalacturonan acetylesterase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Rhamnogalacturonan acetylesterase | Authors: | Langkilde, A, Lo Leggio, L, Navarro Poulsen, J.C, Molgaard, A, Larsen, S. | Deposit date: | 2008-01-24 | Release date: | 2008-08-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Short strong hydrogen bonds in proteins: a case study of rhamnogalacturonan acetylesterase ACTA CRYSTALLOGR.,SECT.D, 64, 2008
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7P6M
| Hydrogenated refolded hen egg-white lysozyme | Descriptor: | ACETATE ION, Lysozyme C, NITRATE ION | Authors: | Ramos, J, Laux, V, Haertlein, M, Forsyth, V.T, Mossou, E, Larsen, S, Langkilde, A.E. | Deposit date: | 2021-07-16 | Release date: | 2021-12-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.89 Å) | Cite: | The impact of folding modes and deuteration on the atomic resolution structure of hen egg-white lysozyme. Acta Crystallogr D Struct Biol, 77, 2021
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4CAG
| Bacillus licheniformis Rhamnogalacturonan Lyase PL11 | Descriptor: | CALCIUM ION, GLYCEROL, POLYSACCHARIDE LYASE FAMILY 11 PROTEIN | Authors: | Otten, H, Rodrigues da Silva, I.I.C, Jers, C, Nyffenegger, C, Larsen, D.M, Mikkelsen, J.D, Larsen, S. | Deposit date: | 2013-10-08 | Release date: | 2014-10-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Design of Thermostable Rhamnogalacturonan Lyase Mutants from Bacillus Licheniformis by Combination of Targeted Single Point Mutations. Appl.Microbiol.Biotechnol., 98, 2014
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1OVD
| THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE | Descriptor: | DIHYDROOROTATE DEHYDROGENASE A, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | Deposit date: | 2003-03-26 | Release date: | 2003-08-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function. J.Biol.Chem., 278, 2003
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1PP4
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3ZSC
| Catalytic function and substrate recognition of the pectate lyase from Thermotoga maritima | Descriptor: | 4-deoxy-beta-L-threo-hex-4-enopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid, GLYCEROL, PECTATE TRISACCHARIDE-LYASE, ... | Authors: | McDonough, M.A, Thymark, M, Frisner, H, Hotchkiss, A, Sonksen, C, Bjornvad, M, Johansen, K.S, Larsen, S. | Deposit date: | 2011-06-24 | Release date: | 2012-07-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Catalytic Function and Substrate Recognition of the Pectate Lyase from Thermotoga Maritima To be Published
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3NJX
| Rhamnogalacturonan Lyase from Aspergillus aculeatus mutant H210A | Descriptor: | CALCIUM ION, Rhamnogalacturonase B, SULFATE ION | Authors: | Jensen, M.H, Otten, H, Christensen, U, Borchert, T.V, Christensen, L.L.H, Larsen, S, Lo Leggio, L. | Deposit date: | 2010-06-18 | Release date: | 2010-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural and Biochemical Studies Elucidate the Mechanism of Rhamnogalacturonan Lyase from Aspergillus aculeatus. J.Mol.Biol., 404, 2010
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3NJV
| Rhamnogalacturonan lyase from Aspergillus aculeatus K150A substrate complex | Descriptor: | CALCIUM ION, Rhamnogalacturonase B, SULFATE ION, ... | Authors: | Jensen, M.H, Otten, H, Christensen, U, Borchert, T.V, Christensen, L.L.H, Larsen, S, Lo Leggio, L. | Deposit date: | 2010-06-18 | Release date: | 2010-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and Biochemical Studies Elucidate the Mechanism of Rhamnogalacturonan Lyase from Aspergillus aculeatus. J.Mol.Biol., 404, 2010
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2V9X
| E138D variant of Escherichia coli dCTP deaminase in complex with dUTP | Descriptor: | DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, DEOXYURIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Thymark, M, Johansson, E, Larsen, S, Willemoes, M. | Deposit date: | 2007-08-28 | Release date: | 2007-11-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mutational Analysis of the Nucleotide Binding Site of Escherichia Coli Dctp Deaminase. Arch.Biochem.Biophys., 470, 2008
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3GTX
| D71G/E101G mutant in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-28 | Release date: | 2009-06-30 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3GTI
| D71G/E101G/M234L mutant in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, Organophosphorus hydrolase, SODIUM ION | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-27 | Release date: | 2009-06-30 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3GTH
| D71G/E101G/M234I mutant in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, FORMIC ACID, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-27 | Release date: | 2009-06-30 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3GU1
| Y97W mutant in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, GLYCEROL, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-28 | Release date: | 2009-06-30 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3GU2
| Y97L/G100-/E101- mutant in organophosphorus hydrolase | Descriptor: | COBALT (II) ION, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-28 | Release date: | 2009-06-30 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3GU9
| R228A mutation in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-28 | Release date: | 2009-06-30 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3GTF
| D71G/E101G/V235L mutant in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-27 | Release date: | 2009-06-30 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3HTW
| Organophosphorus hydrolase from Deinococcus radiodurans with cacodylate bound | Descriptor: | CACODYLATE ION, COBALT (II) ION, MAGNESIUM ION, ... | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-06-12 | Release date: | 2009-06-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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1EP3
| CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B. DATA COLLECTED UNDER CRYOGENIC CONDITIONS. | Descriptor: | DIHYDROOROTATE DEHYDROGENASE B (PYRD SUBUNIT), DIHYDROOROTATE DEHYDROGENASE B (PYRK SUBUNIT), FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Rowland, P, Norager, S, Jensen, K.F, Larsen, S. | Deposit date: | 2000-03-27 | Release date: | 2001-01-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of dihydroorotate dehydrogenase B: electron transfer between two flavin groups bridged by an iron-sulphur cluster. Structure Fold.Des., 8, 2000
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2XHN
| Rhamnogalacturonan lyase from Aspergillus aculeatus K150A active site mutant | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, RHAMNOGALACTURONASE B, ... | Authors: | Jensen, M.H, Otten, H, Christensen, U, Borchert, T.V, Christensen, L.L.H, Larsen, S, Lo Leggio, L. | Deposit date: | 2010-06-18 | Release date: | 2010-09-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structural and Biochemical Studies Elucidate the Mechanism of Rhamnogalacturonan Lyase from Aspergillus Aculeatus. J.Mol.Biol., 404, 2010
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1DKR
| CRYSTAL STRUCTURES OF BACILLUS SUBTILIS PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE: MOLECULAR BASIS OF ALLOSTERIC INHIBITION AND ACTIVATION. | Descriptor: | PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE, SULFATE ION | Authors: | Eriksen, T.A, Kadziola, A, Bentsen, A.-K, Harlow, K.W, Larsen, S. | Deposit date: | 1999-12-08 | Release date: | 2000-04-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the function of Bacillus subtilis phosphoribosyl-pyrophosphate synthetase. Nat.Struct.Biol., 7, 2000
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1F76
| ESCHERICHIA COLI DIHYDROOROTATE DEHYDROGENASE | Descriptor: | Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, FORMIC ACID, ... | Authors: | Norager, S, Jensen, K.F, Bjornberg, O, Larsen, S. | Deposit date: | 2000-06-26 | Release date: | 2002-10-16 | Last modified: | 2014-03-12 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | E. coli Dihydroorotate Dehydrogenase Reveals Structural and Functional Distinction between different classes of
dihydroorotate dehydrogenases Structure, 10, 2002
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1RMG
| RHAMNOGALACTURONASE A FROM ASPERGILLUS ACULEATUS | Descriptor: | RHAMNOGALACTURONASE A, alpha-D-glucopyranose, alpha-D-mannopyranose, ... | Authors: | Petersen, T.N, Kauppinen, S, Larsen, S. | Deposit date: | 1997-02-26 | Release date: | 1998-03-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of rhamnogalacturonase A from Aspergillus aculeatus: a right-handed parallel beta helix. Structure, 5, 1997
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1DKU
| CRYSTAL STRUCTURES OF BACILLUS SUBTILIS PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE: MOLECULAR BASIS OF ALLOSTERIC INHIBITION AND ACTIVATION. | Descriptor: | METHYL PHOSPHONIC ACID ADENOSINE ESTER, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, PROTEIN (PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE) | Authors: | Eriksen, T.A, Kadziola, A, Bentsen, A.-K, Harlow, K.W, Larsen, S. | Deposit date: | 1999-12-08 | Release date: | 2000-04-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the function of Bacillus subtilis phosphoribosyl-pyrophosphate synthetase. Nat.Struct.Biol., 7, 2000
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