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6CCX
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BU of 6ccx by Molmil
NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc
Descriptor: (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ...
Authors:Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M.
Deposit date:2018-02-07
Release date:2018-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
6CCH
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BU of 6cch by Molmil
NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ...
Authors:Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M.
Deposit date:2018-02-07
Release date:2018-08-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
6D83
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BU of 6d83 by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Buffalo, C.Z, Morris, K.L, Hurley, J.H.
Deposit date:2018-04-25
Release date:2018-08-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6CC9
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BU of 6cc9 by Molmil
NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc
Descriptor: (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ...
Authors:Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M.
Deposit date:2018-02-06
Release date:2018-09-05
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
6C4S
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BU of 6c4s by Molmil
Human cSrc SH3 Domain in complex with Choline Kinase fragment 60-69
Descriptor: Proto-oncogene tyrosine-protein kinase Src,cSrc SH3 Domain, ZINC ION
Authors:Kall, S.L, Lavie, A.
Deposit date:2018-01-12
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase.
Sci Rep, 9, 2019
6CIT
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BU of 6cit by Molmil
Crystal Structure of MVM NS2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2018-02-25
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.027 Å)
Cite:Correlation of CRM1-NES affinity with nuclear export activity.
Mol. Biol. Cell, 29, 2018
6CRI
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BU of 6cri by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Morris, K.L, Buffalo, C.Z, Hurley, J.H.
Deposit date:2018-03-18
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6EKJ
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BU of 6ekj by Molmil
Crystal structure of mammalian Rev7 in complex with human Chromosome alignment-maintaining phosphoprotein 1
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T.
Deposit date:2017-09-26
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of mammalian Rev7 in complex with Champ1 - CAPS molecule
To Be Published
6EKM
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BU of 6ekm by Molmil
Crystal structure of mammalian Rev7 in complex with human Rev3 second binding site
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T.
Deposit date:2017-09-26
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Crystal structure of mammalian Rev7 in complex with human Rev3
To Be Published
6ENY
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BU of 6eny by Molmil
Structure of the human PLC editing module
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ...
Authors:Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R.
Deposit date:2017-10-07
Release date:2017-11-29
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structure of the human MHC-I peptide-loading complex.
Nature, 551, 2017
6EKL
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BU of 6ekl by Molmil
Crystal structure of mammalian Rev7 in complex with human Chromosome alignment-maintaining phosphoprotein 1
Descriptor: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T.
Deposit date:2017-09-26
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of mammalian Rev7 in complex with Champ1
To Be Published
5Y39
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BU of 5y39 by Molmil
Crystal structure of Ragulator complex (p18 76-145)
Descriptor: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ...
Authors:Zhang, T, Ding, J.
Deposit date:2017-07-28
Release date:2017-12-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1
Nat Commun, 8, 2017
6DFF
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BU of 6dff by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H.
Deposit date:2018-05-14
Release date:2018-08-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6D84
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BU of 6d84 by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Buffalo, C.Z, Morris, K.L, Hurley, J.H.
Deposit date:2018-04-25
Release date:2018-08-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.72 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6FAE
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BU of 6fae by Molmil
The Sec7 domain of IQSEC2 (Brag1) in complex with the small GTPase Arf1
Descriptor: 1,2-ETHANEDIOL, ADP-ribosylation factor 1, IQ motif and SEC7 domain-containing protein 2
Authors:Gray, J, Krojer, T, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P, von Delft, F.
Deposit date:2017-12-15
Release date:2018-01-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Targeting the Small GTPase Superfamily through their Regulatory Proteins.
Angew.Chem.Int.Ed.Engl., 2019
4HVV
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BU of 4hvv by Molmil
Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide APP12
Descriptor: Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, SYNTHETIC PEPTIDE Acetyl-APPLPPRNRP
Authors:Camara-Artigas, A.
Deposit date:2012-11-07
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II.
Acta Crystallogr.,Sect.D, 69, 2013
4HVW
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BU of 4hvw by Molmil
Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide VSL12
Descriptor: ACETYL GROUP, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ...
Authors:Camara-Artigas, A.
Deposit date:2012-11-07
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II.
Acta Crystallogr.,Sect.D, 69, 2013
4HVU
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BU of 4hvu by Molmil
Crystal structure of the T98D c-Src-SH3 domain mutant in complex with the high affinity peptide APP12
Descriptor: ACETYL GROUP, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ...
Authors:Camara-Artigas, A.
Deposit date:2012-11-07
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II.
Acta Crystallogr.,Sect.D, 69, 2013
2KOJ
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BU of 2koj by Molmil
Solution structure of mouse Par-3 PDZ2 (residues 450-558)
Descriptor: Partitioning defective 3 homolog
Authors:Volkman, B.F, Tyler, R.C, Peterson, F.C, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2009-09-23
Release date:2009-11-10
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Macromolecular Structure Determination by NMR Sepectroscopy
Structural Bioinformatics, 2nd edition, 2009
2CQA
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BU of 2cqa by Molmil
Solution structure of RSGI RUH-039, a fragment of C-terminal domain of RuvB-like 2 from human cDNA
Descriptor: RuvB-like 2
Authors:Abe, T, Hirota, H, Saito, K, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-19
Release date:2005-11-19
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of RSGI RUH-039, a fragment of C-terminal domain of RuvB-like 2 from human cDNA
To be Published
2K6Q
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BU of 2k6q by Molmil
LC3 p62 complex structure
Descriptor: Microtubule-associated proteins 1A/1B light chain 3B, p62_peptide from Sequestosome-1
Authors:Noda, N, Kumeta, H, Nakatogawa, H, Satoo, K, Adachi, W, Ishii, J, Fujioka, Y, Ohsumi, Y, Inagaki, F.
Deposit date:2008-07-17
Release date:2008-09-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis of target recognition by ATG8/LC3 during selective autophagy
To be Published
2KTR
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BU of 2ktr by Molmil
NMR structure of p62 PB1 dimer determined based on PCS
Descriptor: Sequestosome-1, TERBIUM(III) ION
Authors:Saio, T, Yokochi, M, Kumeta, H, Inagaki, F.
Deposit date:2010-02-05
Release date:2010-04-07
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:PCS-based structure determination of protein-protein complexes
J.Biomol.Nmr, 46, 2010
2KKC
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BU of 2kkc by Molmil
NMR structure of the p62 PB1 domain
Descriptor: Sequestosome-1
Authors:Yokochi, M, Inagaki, F.
Deposit date:2009-06-18
Release date:2009-09-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The NMR structure of the p62 PB1 domain, a key protein in autophagy and NF-kappaB signaling pathway
J.Biomol.Nmr, 45, 2009
2KWH
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BU of 2kwh by Molmil
Ral binding domain of RLIP76 (RalBP1)
Descriptor: RalA-binding protein 1
Authors:Fenwick, R.B, Campbell, L.J, Rajasekar, K, Prasannan, S, Nietlispach, D, Camonis, J, Owen, D, Mott, H.R.
Deposit date:2010-04-12
Release date:2010-09-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction
Structure, 18, 2010
4J0U
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BU of 4j0u by Molmil
Crystal structure of IFIT5/ISG58
Descriptor: Interferon-induced protein with tetratricopeptide repeats 5
Authors:Liu, Y, Liang, H, Feng, F, Yuan, L, Wang, Y.E, Crowley, C, Lv, Z, Li, J, Zeng, S, Cheng, G.
Deposit date:2013-01-31
Release date:2013-02-13
Method:X-RAY DIFFRACTION (1.969 Å)
Cite:Crystal Structure of IFIT5
To be Published

223532

數據於2024-08-07公開中

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