6CIT

Crystal Structure of MVM NS2 NES Peptide in complex with CRM1-Ran-RanBP1

Summary for 6CIT

• Entry DOI: 10.2210/pdb6cit/pdb
• Descriptor: GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ... (9 entities in total)
• Functional Keywords: karyopherin, crm1, xpo1, exportin-1, mvm, nes, nuclear export, protein transport
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 164164.26

Authors

Fung, H.Y.J.,Chook, Y.M. (deposition date: 2018-02-25, release date: 2018-06-27, Last modification date: 2023-10-04)

• Primary citation: Fu, S.C.,Fung, H.Y.J.,Cagatay, T.,Baumhardt, J.,Chook, Y.M.; Correlation of CRM1-NES affinity with nuclear export activity.; Mol. Biol. Cell, 29:2037-2044, 2018; PubMed: 29927350; DOI: 10.1091/mbc.E18-02-0096

Experimental method

X-RAY DIFFRACTION (2.027 Å)