6FAE
The Sec7 domain of IQSEC2 (Brag1) in complex with the small GTPase Arf1
Summary for 6FAE
| Entry DOI | 10.2210/pdb6fae/pdb |
| Descriptor | IQ motif and SEC7 domain-containing protein 2, ADP-ribosylation factor 1, 1,2-ETHANEDIOL, ... (4 entities in total) |
| Functional Keywords | gtpase gef, hydrolase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 67448.08 |
| Authors | Gray, J.,Krojer, T.,Fairhead, M.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,Brennan, P.,von Delft, F. (deposition date: 2017-12-15, release date: 2018-01-17, Last modification date: 2019-04-24) |
| Primary citation | Gray, J.L.,von Delft, F.,Brennan, P. Targeting the Small GTPase Superfamily through their Regulatory Proteins. Angew.Chem.Int.Ed.Engl., 2019 Cited by PubMed: 30869179DOI: 10.1002/anie.201900585 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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