6FAE

The Sec7 domain of IQSEC2 (Brag1) in complex with the small GTPase Arf1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005085	molecular_function	guanyl-nucleotide exchange factor activity
A	0032012	biological_process	regulation of ARF protein signal transduction
B	0000139	cellular_component	Golgi membrane
B	0000287	molecular_function	magnesium ion binding
B	0002090	biological_process	regulation of receptor internalization
B	0003723	molecular_function	RNA binding
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0005925	cellular_component	focal adhesion
B	0006878	biological_process	intracellular copper ion homeostasis
B	0006886	biological_process	intracellular protein transport
B	0012505	cellular_component	endomembrane system
B	0014069	cellular_component	postsynaptic density
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0016192	biological_process	vesicle-mediated transport
B	0016787	molecular_function	hydrolase activity
B	0019904	molecular_function	protein domain specific binding
B	0030017	cellular_component	sarcomere
B	0031252	cellular_component	cell leading edge
B	0032991	cellular_component	protein-containing complex
B	0034315	biological_process	regulation of Arp2/3 complex-mediated actin nucleation
B	0043005	cellular_component	neuron projection
B	0045202	cellular_component	synapse
B	0060292	biological_process	long-term synaptic depression
B	0070062	cellular_component	extracellular exosome
B	0097061	biological_process	dendritic spine organization
B	0098586	biological_process	cellular response to virus
B	1990386	biological_process	mitotic cleavage furrow ingression

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue EDO B 201

Chain	Residue
A	ARG565
A	VAL567
B	LYS73
B	PRO76

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:7990966, ECO:0007744|PDB:1HUR

Chain	Residue	Details
B	GLY24
A	ARG403

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:14690595, ECO:0000269|PubMed:15308674, ECO:0000269|PubMed:7990966, ECO:0000269|Ref.34, ECO:0007744|PDB:1HUR, ECO:0007744|PDB:1RE0, ECO:0007744|PDB:1U81, ECO:0007744|PDB:3O47

Chain	Residue	Details
B	ASN126

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:15308674, ECO:0000269|PubMed:7990966, ECO:0000269|Ref.34, ECO:0007744|PDB:1HUR, ECO:0007744|PDB:1RE0, ECO:0007744|PDB:3O47

Chain	Residue	Details
B	ALA160

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