6FAE
The Sec7 domain of IQSEC2 (Brag1) in complex with the small GTPase Arf1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| A | 0032012 | biological_process | regulation of ARF protein signal transduction |
| B | 0000139 | cellular_component | Golgi membrane |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0002090 | biological_process | regulation of receptor internalization |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0003925 | molecular_function | G protein activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0005925 | cellular_component | focal adhesion |
| B | 0006878 | biological_process | intracellular copper ion homeostasis |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0012505 | cellular_component | endomembrane system |
| B | 0014069 | cellular_component | postsynaptic density |
| B | 0015031 | biological_process | protein transport |
| B | 0016192 | biological_process | vesicle-mediated transport |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019904 | molecular_function | protein domain specific binding |
| B | 0030017 | cellular_component | sarcomere |
| B | 0031252 | cellular_component | cell leading edge |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0034315 | biological_process | regulation of Arp2/3 complex-mediated actin nucleation |
| B | 0043005 | cellular_component | neuron projection |
| B | 0045202 | cellular_component | synapse |
| B | 0060292 | biological_process | long-term synaptic depression |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0097061 | biological_process | dendritic spine organization |
| B | 0098586 | biological_process | cellular response to virus |
| B | 1990386 | biological_process | mitotic cleavage furrow ingression |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 201 |
| Chain | Residue |
| A | ARG565 |
| A | VAL567 |
| B | LYS73 |
| B | PRO76 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"7990966","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HUR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15308674","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7990966","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2010","submissionDatabase":"PDB data bank","title":"Crystal structure of ARFGAP1-ARF1 fusion protein.","authoringGroup":["Structural genomics consortium (SGC)."]}},{"source":"PDB","id":"1HUR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RE0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3O47","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
