3EGU
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![BU of 3egu by Molmil](/molmil-images/mine/3egu) | Crystal structure of the N114A mutant of ABL-SH3 domain | Descriptor: | GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1, SULFATE ION | Authors: | Camara-Artigas, A. | Deposit date: | 2008-09-11 | Release date: | 2009-09-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285, 2010
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4ONL
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![BU of 4onl by Molmil](/molmil-images/mine/4onl) | Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P | Descriptor: | Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 | Authors: | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | Deposit date: | 2014-01-28 | Release date: | 2015-05-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
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3E7A
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![BU of 3e7a by Molmil](/molmil-images/mine/3e7a) | Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin Nodularin-R | Descriptor: | AZIDE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Kelker, M.S, Page, R, Peti, W. | Deposit date: | 2008-08-18 | Release date: | 2008-11-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors J.Mol.Biol., 385, 2009
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3WJL
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![BU of 3wjl by Molmil](/molmil-images/mine/3wjl) | Crystal structure of IIb selective Fc variant, Fc(V12), in complex with FcgRIIb | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-c, ... | Authors: | Kadono, S, Mimoto, F, Katada, H, Igawa, T, Kuramochi, T, Muraoka, M, Wada, Y, Haraya, K, Miyazaki, T, Hattori, K. | Deposit date: | 2013-10-11 | Release date: | 2013-11-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Engineered antibody Fc variant with selectively enhanced Fc gamma RIIb binding over both Fc gamma RIIaR131 and Fc gamma RIIaH131. Protein Eng.Des.Sel., 26, 2013
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3EIO
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![BU of 3eio by Molmil](/molmil-images/mine/3eio) | Crystal Structure Analysis of DPPIV Inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-({4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-1,4-diazepan-1-yl}carbonyl)benzoic acid, ... | Authors: | Ahn, J.H, Lee, J.-O. | Deposit date: | 2008-09-17 | Release date: | 2008-11-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors Bioorg.Med.Chem.Lett., 18, 2008
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4OTD
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![BU of 4otd by Molmil](/molmil-images/mine/4otd) | Crystal Structure of PRK1 Catalytic Domain | Descriptor: | Serine/threonine-protein kinase N1 | Authors: | Chamberlain, P.P, Delker, S, Pagarigan, B, Mahmoudi, A, Jackson, P, Abbassian, M, Muir, J, Raheja, N, Cathers, B. | Deposit date: | 2014-02-13 | Release date: | 2014-08-27 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes. Plos One, 9, 2014
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3EJI
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![BU of 3eji by Molmil](/molmil-images/mine/3eji) | Crystal structure of Staphylococcal nuclease variant Delta+PHS L36K at cryogenic temperature | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Thermonuclease | Authors: | Khangulov, V.S, Schlessman, J.L, Garcia-Moreno, E.B, Benning, M, Isom, D. | Deposit date: | 2008-09-18 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Consequences of the Ionization of Lysines at 25 Internal Positions in a Protein To be Published
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3EKP
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![BU of 3ekp by Molmil](/molmil-images/mine/3ekp) | Crystal Structure of the inhibitor Amprenavir (APV) in complex with a multi-drug resistant HIV-1 protease variant (L10I/G48V/I54V/V64I/V82A)Refer: FLAP+ in citation | Descriptor: | ACETATE ION, PHOSPHATE ION, Protease, ... | Authors: | Prabu-Jayabalan, M, King, N.M, Bandaranayake, R.M. | Deposit date: | 2008-09-19 | Release date: | 2009-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Extreme Entropy-Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 Protease. Acs Chem.Biol., 7, 2012
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3E9Z
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![BU of 3e9z by Molmil](/molmil-images/mine/3e9z) | Crystal structure of purine nucleoside phosphorylase from Schistosoma mansoni in complex with 6-chloroguanine | Descriptor: | 6-chloroguanine, ACETATE ION, DIMETHYL SULFOXIDE, ... | Authors: | Pereira, H.M, Rezende, M.M, Oliva, G, Garratt, R.C. | Deposit date: | 2008-08-24 | Release date: | 2009-09-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase (SmPNP) in complex with adenine, 8-aminoguanine, 8-azaguanine and 6-chloroguanine. To be Published
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3EMK
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![BU of 3emk by Molmil](/molmil-images/mine/3emk) | |
3EEI
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![BU of 3eei by Molmil](/molmil-images/mine/3eei) | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from neisseria meningitidis in complex with methylthio-immucillin-A | Descriptor: | (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase | Authors: | Ho, M, Rinaldo-matthis, A, Brown, R.L, Norris, G.E, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L. | Deposit date: | 2008-09-04 | Release date: | 2009-09-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from neisseria meningitidis in complex with methylthio-immucillin-A To be Published
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3EKH
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![BU of 3ekh by Molmil](/molmil-images/mine/3ekh) | Calcium-saturated GCaMP2 T116V/K378W mutant monomer | Descriptor: | CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | Deposit date: | 2008-09-19 | Release date: | 2008-12-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design J.Biol.Chem., 284, 2009
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3E2E
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![BU of 3e2e by Molmil](/molmil-images/mine/3e2e) | Crystal Structure of an Intermediate Complex of T7 RNAP and 7nt of RNA | Descriptor: | DNA (28-MER), DNA (31-MER), DNA-directed RNA polymerase, ... | Authors: | Durniak, K.J, Bailey, S, Steitz, T.A. | Deposit date: | 2008-08-05 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of a transcribing t7 RNA polymerase in transition from initiation to elongation Science, 322, 2008
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3E2A
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3EDG
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![BU of 3edg by Molmil](/molmil-images/mine/3edg) | |
3E5O
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![BU of 3e5o by Molmil](/molmil-images/mine/3e5o) | Carbonmonoxy Sperm Whale Myoglobin at 140 K: Laser off | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Tomita, A, Sato, T, Ichiyanagi, K, Nozawa, S, Ichikawa, H, Chollet, M, Kawai, F, Park, S.-Y, Koshihara, S, Adachi, S. | Deposit date: | 2008-08-14 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin. Proc.Natl.Acad.Sci.USA, 106, 2009
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3FVT
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![BU of 3fvt by Molmil](/molmil-images/mine/3fvt) | |
4P6A
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![BU of 4p6a by Molmil](/molmil-images/mine/4p6a) | Crystal structure of a potent anti-HIV lectin actinohivin in complex with alpha-1,2-mannotriose | Descriptor: | Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | Authors: | Zhang, F, Hoque, M.M, Suzuki, K, Tsunoda, M, Naomi, O, Tanaka, H, Takenaka, A. | Deposit date: | 2014-03-23 | Release date: | 2015-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.398 Å) | Cite: | The characteristic structure of anti-HIV actinohivin in complex with three HMTG D1 chains of HIV-gp120. Chembiochem, 15, 2014
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3G0A
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![BU of 3g0a by Molmil](/molmil-images/mine/3g0a) | Mth0212 with two bound manganese ions | Descriptor: | Exodeoxyribonuclease, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Lakomek, K, Dickmanns, A, Ficner, R. | Deposit date: | 2009-01-27 | Release date: | 2010-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA J.Mol.Biol., 399, 2010
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3G1E
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![BU of 3g1e by Molmil](/molmil-images/mine/3g1e) | X-ray crystal structure of coil 1A of human vimentin | Descriptor: | Vimentin | Authors: | Meier, M, Padilla, G.P, Herrmann, H, Wedig, T, Hergt, M, Patel, T.R, Stetefeld, J, Aebi, U, Burkhard, P. | Deposit date: | 2009-01-29 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation. J.Mol.Biol., 390, 2009
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4OV4
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![BU of 4ov4 by Molmil](/molmil-images/mine/4ov4) | Isopropylmalate synthase binding with ketoisovalerate | Descriptor: | 2-isopropylmalate synthase, 3-METHYL-2-OXOBUTANOIC ACID, ZINC ION | Authors: | Zhang, Z, Wu, J, Wang, C, Zhang, P. | Deposit date: | 2014-02-20 | Release date: | 2014-08-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition. J.Biol.Chem., 289, 2014
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3GCO
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![BU of 3gco by Molmil](/molmil-images/mine/3gco) | |
4OOJ
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![BU of 4ooj by Molmil](/molmil-images/mine/4ooj) | Crystal structure of the N-terminal domain of the Legionella pneumophila protein SidC at 2.4A resolution | Descriptor: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, SidC, ... | Authors: | Gazdag, E.M, Shoebel, S, Shkumatov, A.V, Goody, R.S, Itzen, A. | Deposit date: | 2014-02-03 | Release date: | 2014-02-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The structure of the N-terminal domain of the Legionella protein SidC J.Struct.Biol., 186, 2014
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4O8S
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3V51
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![BU of 3v51 by Molmil](/molmil-images/mine/3v51) | |