3GCO

Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with DNRDGNVYQF OMP peptide

Summary for 3GCO

Entry DOI	10.2210/pdb3gco/pdb
Related	3GCN 3GDS 3GDU 3GDV
Descriptor	Protease degS, DNRDGNVYQF peptide (2 entities in total)
Functional Keywords	protease, stress-sensor, htra, pdz omp, allostery, hydrolase, serine protease, hydrolase-hydrolase activator complex, hydrolase/hydrolase activator
Biological source	Escherichia coli
Cellular location	Cell inner membrane ; Single-pass membrane protein : P0AEE3
Total number of polymer chains	2
Total formula weight	37486.04
Authors	Sohn, J.,Grant, R.A.,Sauer, R.T. (deposition date: 2009-02-22, release date: 2009-03-31, Last modification date: 2021-10-20)
Primary citation	Sohn, J.,Grant, R.A.,Sauer, R.T. OMP peptides activate the DegS stress-sensor protease by a relief of inhibition mechanism. Structure, 17:1411-1421, 2009 Cited by PubMed: 19836340 DOI: 10.1016/j.str.2009.07.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.798 Å)

Structure validation