4OV4

Isopropylmalate synthase binding with ketoisovalerate

Summary for 4OV4

• Entry DOI: 10.2210/pdb4ov4/pdb
• Related: 4OV9
• Descriptor: 2-isopropylmalate synthase, ZINC ION, 3-METHYL-2-OXOBUTANOIC ACID, ... (4 entities in total)
• Functional Keywords: alpha/beta tim barrel, transferase
• Biological source: Leptospira biflexa
• Total number of polymer chains: 1
• Total formula weight: 46332.79

Authors

Zhang, Z.,Wu, J.,Wang, C.,Zhang, P. (deposition date: 2014-02-20, release date: 2014-08-20, Last modification date: 2024-03-20)

• Primary citation: Zhang, Z.,Wu, J.,Lin, W.,Wang, J.,Yan, H.,Zhao, W.,Ma, J.,Ding, J.,Zhang, P.,Zhao, G.P.; Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition.; J.Biol.Chem., 289:27966-27978, 2014; PubMed: 25128527; DOI: 10.1074/jbc.M114.559716

Experimental method

X-RAY DIFFRACTION (2 Å)