3EIO
Crystal Structure Analysis of DPPIV Inhibitor
Summary for 3EIO
Entry DOI | 10.2210/pdb3eio/pdb |
Descriptor | Dipeptidyl peptidase 4 soluble form, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | protein-inhibitor complex, aminopeptidase, cell membrane, glycoprotein, hydrolase, membrane, protease, secreted, serine protease, signal-anchor, transmembrane |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 174772.76 |
Authors | Ahn, J.H.,Lee, J.-O. (deposition date: 2008-09-17, release date: 2008-11-04, Last modification date: 2020-07-29) |
Primary citation | Ahn, J.H.,Park, W.S.,Jun, M.A.,Shin, M.S.,Kang, S.K.,Kim, K.Y.,Rhee, S.D.,Bae, M.A.,Kim, K.R.,Kim, S.G.,Kim, S.Y.,Sohn, S.K.,Kang, N.S.,Lee, J.O.,Lee, D.H.,Cheon, H.G.,Kim, S.S. Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors Bioorg.Med.Chem.Lett., 18:6525-6529, 2008 Cited by PubMed: 18996694DOI: 10.1016/j.bmcl.2008.10.076 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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