4P6A

Crystal structure of a potent anti-HIV lectin actinohivin in complex with alpha-1,2-mannotriose

Replaces:  4G1S

Summary for 4P6A

• Entry DOI: 10.2210/pdb4p6a/pdb
• Descriptor: Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose (3 entities in total)
• Functional Keywords: actinohivin, anti-hiv lectin, high-mannose type glycan, sugar binding protein
• Biological source: Actinomycete sp.
• Total number of polymer chains: 1
• Total formula weight: 14045.81

Authors

Zhang, F.,Hoque, M.M.,Suzuki, K.,Tsunoda, M.,Naomi, O.,Tanaka, H.,Takenaka, A. (deposition date: 2014-03-23, release date: 2015-03-04, Last modification date: 2023-12-27)

• Primary citation: Zhang, F.,Hoque, M.M.,Jiang, J.,Suzuki, K.,Tsunoda, M.,Takeda, Y.,Ito, Y.,Kawai, G.,Tanaka, H.,Takenaka, A.; The characteristic structure of anti-HIV actinohivin in complex with three HMTG D1 chains of HIV-gp120.; Chembiochem, 15:2766-2773, 2014; PubMed: 25403811; DOI: 10.1002/cbic.201402352

Experimental method

X-RAY DIFFRACTION (1.398 Å)