4ONL
Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P
Summary for 4ONL
Entry DOI | 10.2210/pdb4onl/pdb |
Related | 4ONM 4ONN |
Descriptor | Ubiquitin-conjugating enzyme E2 variant 2, Ubiquitin-conjugating enzyme E2 N (3 entities in total) |
Functional Keywords | ubc13, mms2, e2, ubiquitin conjugating enzyme, ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P61088 |
Total number of polymer chains | 2 |
Total formula weight | 35048.19 |
Authors | Hodge, C.D.,Edwards, R.A.,Glover, J.N.M. (deposition date: 2014-01-28, release date: 2015-05-06, Last modification date: 2024-02-28) |
Primary citation | Hodge, C.D.,Edwards, R.A.,Markin, C.J.,McDonald, D.,Pulvino, M.,Huen, M.S.,Zhao, J.,Spyracopoulos, L.,Hendzel, M.J.,Glover, J.N. Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10:1718-1728, 2015 Cited by PubMed: 25909880DOI: 10.1021/acschembio.5b00222 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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