4ONL

Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ubiquitin-conjugating enzyme E2 variant 2	polymer	153	17165.6	1	UniProt (Q15819) Pfam (PF00179) In PDB	Homo sapiens (human)	DDVit 1, Enterocyte differentiation-associated factor 1, EDAF-1, Enterocyte differentiation-promoting factor 1, EDPF-1, MMS2 homolog, Vitamin D3-inducible protein
2	B	Ubiquitin-conjugating enzyme E2 N	polymer	160	17882.6	1	UniProt (P61088) Pfam (PF00179) In PDB	Homo sapiens (human)	Bendless-like ubiquitin-conjugating enzyme, Ubc13, UbcH13, Ubiquitin carrier protein N, Ubiquitin-protein ligase N
3		water	water		18.0	197	Chemie (HOH)

Sequence modifications

A: 1 - 145 (UniProt: Q15819)

PDB	External Database	Details
Gly -7	-	expression tag
Pro -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

B: 1 - 152 (UniProt: P61088)

PDB	External Database	Details
Gly -7	-	expression tag
Pro -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag
Asn 81	Asp 81	conflict
Ser 85	Arg 85	engineered mutation
Val 122	Ala 122	engineered mutation
Pro 123	Asn 123	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35048.2
All*	Total formula weight	35048.2

*Water molecules are not included.