3EEI

Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from neisseria meningitidis in complex with methylthio-immucillin-A

Summary for 3EEI

• Entry DOI: 10.2210/pdb3eei/pdb
• Descriptor: 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase, (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL (3 entities in total)
• Functional Keywords: mtan, 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase, immucillin a, glycosidase, hydrolase
• Biological source: Neisseria meningitidis serogroup B
• Total number of polymer chains: 2
• Total formula weight: 50043.36

Authors

Ho, M.,Rinaldo-matthis, A.,Brown, R.L.,Norris, G.E.,Tyler, P.C.,Furneaux, R.H.,Almo, S.C.,Schramm, V.L. (deposition date: 2008-09-04, release date: 2009-09-08, Last modification date: 2024-02-21)

• Primary citation: Ho, M.,Rinaldo-matthis, A.,Brown, R.L.,Norris, G.E.,Tyler, P.C.,Furneaux, R.H.,Almo, S.C.,Schramm, V.L.; Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from neisseria meningitidis in complex with methylthio-immucillin-A; To be Published,

Experimental method

X-RAY DIFFRACTION (1.78 Å)