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2CDF
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BU of 2cdf by Molmil
Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide-specific T cell receptors (TCR 5E)
Descriptor: TCR 5E
Authors:Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y.
Deposit date:2006-01-23
Release date:2006-03-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
1T2J
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BU of 1t2j by Molmil
Crystal structure of a Human VH domain
Descriptor: DI(HYDROXYETHYL)ETHER, M12-Variable Heavy domain
Authors:Gaur, R.K, Fischer, R, Hoffmann, K.M.V.
Deposit date:2004-04-21
Release date:2005-05-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of a human VH domain at 1.5 angstrom
To be Published
1T8D
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BU of 1t8d by Molmil
Structure of the C-type lectin domain of CD23
Descriptor: Low affinity immunoglobulin epsilon Fc receptor
Authors:Hibbert, R.G, Teriete, P, Grundy, G.J, Sutton, B.J, Gould, H.J, McDonnell, J.M.
Deposit date:2004-05-12
Release date:2005-07-26
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:The structure of human CD23 and its interactions with IgE and CD21
J.Exp.Med., 202, 2005
1TRN
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BU of 1trn by Molmil
CRYSTAL STRUCTURE OF HUMAN TRYPSIN 1: UNEXPECTED PHOSPHORYLATION OF TYROSINE 151
Descriptor: PHOSPHORYLISOPROPANE, TRYPSIN
Authors:Gaboriaud, C, Fontecilla-Camps, J.C.
Deposit date:1995-03-16
Release date:1995-06-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human trypsin 1: unexpected phosphorylation of Tyr151.
J.Mol.Biol., 259, 1996
8IV0
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BU of 8iv0 by Molmil
H7N9 HA-C4H4 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C4H4 Fab heavy chain, C4H4 Fab light chain, ...
Authors:Zhao, B.B, Sun, Z.Z.
Deposit date:2023-03-25
Release date:2024-04-24
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:H7N9 HA-C4H4 Fab
To Be Published
5MP3
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BU of 5mp3 by Molmil
Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5
Descriptor: ENSMUSG00000076577 protein, Igh protein, Microtubule-associated protein
Authors:Skrabana, R, Novak, M, Cehlar, O, Kontsekova, E.
Deposit date:2016-12-15
Release date:2018-05-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5
To be published
3OED
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BU of 3oed by Molmil
The structure of the complex between complement receptor CR2 and its ligand complement fragment C3d
Descriptor: Complement C3, Complement receptor type 2
Authors:Isenman, D.E, van den Elsen, J.M.H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:A crystal structure of the complex between human complement receptor 2 and its ligand C3d.
Science, 332, 2011
5N86
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BU of 5n86 by Molmil
Crystal structure of FAS1 domain of hyaluronic acid receptor stabilin-2
Descriptor: Stabilin-2
Authors:Twarda-Clapa, A, Labuzek, B, Grudnik, P, Dubin, G, Holak, T.A.
Deposit date:2017-02-23
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.484 Å)
Cite:Crystal structure of the FAS1 domain of the hyaluronic acid receptor stabilin-2.
Acta Crystallogr D Struct Biol, 74, 2018
7CBC
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BU of 7cbc by Molmil
Crystal structure of a de novo designed switch protein caging a hemagglutinin binder
Descriptor: De novo designed switch protein caging a hemagglutinin binder (sCageHA267_1S), ETHANOL
Authors:Lee, H, Oh, B.-H, Baker, D.
Deposit date:2020-06-11
Release date:2020-12-23
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:De novo design of modular and tunable protein biosensors.
Nature, 591, 2021
8K4Q
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BU of 8k4q by Molmil
Crystal structure of nanobody HuNb103 bound to human interleukin-4 receptor subunit alpha
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IL-4R nanobody HuNb103, ...
Authors:Ding, Y, Zhong, P.Y.
Deposit date:2023-07-20
Release date:2024-06-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:A novel inhalable nanobody targeting IL-4R alpha for the treatment of asthma.
J.Allergy Clin.Immunol., 154, 2024
8KG5
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BU of 8kg5 by Molmil
Prefusion RSV F Bound to Lonafarnib and D25 Fab
Descriptor: 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, D25 heavy chain, D25 light chain, ...
Authors:Yang, Q, Xue, B, Liu, F, Peng, W, Chen, X.
Deposit date:2023-08-17
Release date:2024-06-19
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein.
Signal Transduct Target Ther, 9, 2024
3OY8
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BU of 3oy8 by Molmil
Crystal structure of human galectin-1 in complex with lactobionic acid
Descriptor: Galectin-1, beta-D-galactopyranose-(1-4)-D-gluconic acid
Authors:Blanchard, H, Collins, P.M.
Deposit date:2010-09-23
Release date:2010-11-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
CANCER LETT., 2010
3OYW
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BU of 3oyw by Molmil
Crystal structure of human galectin-1 in complex with thiodigalactoside
Descriptor: Galectin-1, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose
Authors:Blanchard, H, Collins, P.M.
Deposit date:2010-09-23
Release date:2010-11-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
CANCER LETT., 2010
8K3L
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BU of 8k3l by Molmil
SOD1 and Nanobody3 complex
Descriptor: COPPER (II) ION, NB3, Superoxide dismutase [Cu-Zn], ...
Authors:Cheng, S, Liu, R, Ding, Y.
Deposit date:2023-07-16
Release date:2024-07-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:SOD1 and Nanobody1 complex
To Be Published
8K33
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BU of 8k33 by Molmil
SOD1 and Nanobody1 complex
Descriptor: NB1, Superoxide dismutase [Cu-Zn], ZINC ION
Authors:Cheng, S.
Deposit date:2023-07-14
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:SOD1 and Nanobody1 complex
To Be Published
8K3A
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BU of 8k3a by Molmil
SOD1 and Nanobody2 complex
Descriptor: NB2, Superoxide dismutase [Cu-Zn], ZINC ION
Authors:Cheng, S.
Deposit date:2023-07-14
Release date:2024-07-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:SOD1 and Nanobody1 complex
To Be Published
3PGF
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BU of 3pgf by Molmil
Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB)
Descriptor: GLYCEROL, IMIDAZOLE, Maltose-binding periplasmic protein, ...
Authors:Kossiakoff, A.A, Duguid, E.M, Sandstrom, A.
Deposit date:2010-11-01
Release date:2011-03-09
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
Nat.Struct.Mol.Biol., 18, 2011
5O2S
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BU of 5o2s by Molmil
Human KRAS in complex with darpin K27
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Debreczeni, J.E, Guillard, S, Kolasinska-Zwierz, P, Breed, J, Zhang, J, Bery, N, Marwood, R, Tart, J, Stocki, P, Mistry, B, Phillips, C, Rabbitts, T, Jackson, R, Minter, R.
Deposit date:2017-05-22
Release date:2017-07-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange.
Nat Commun, 8, 2017
5O36
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BU of 5o36 by Molmil
Japanese encephalitis virus non-structural protein 1' C-terminal domain
Descriptor: Japanese encephalitis virus non-structural protein 1' (NS1'),Japanese encephalitis virus non-structural protein 1' (NS1'), N-PROPANOL, SULFATE ION
Authors:Thanalai, P, Wright, G.S.A, Antonyuk, S.V.
Deposit date:2017-05-23
Release date:2018-01-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Study of the C-Terminal Domain of Nonstructural Protein 1 from Japanese Encephalitis Virus.
J. Virol., 92, 2018
8P34
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BU of 8p34 by Molmil
Tau filaments extracted from human brain with the DeltaK281 mutation in MAPT
Descriptor: Microtubule-associated protein tau
Authors:Schweighauser, M, Garringer, H.J, Klingstedt, T, Masuda-Suzukake, M, Murrell, J.R, Vidal, R, Scheres, S.H.W, Goedert, M, Ghetti, B, Newell, K.L.
Deposit date:2023-05-17
Release date:2023-07-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Mutation ∆K281 in MAPT causes Pick's disease.
Acta Neuropathol, 146, 2023
5O7P
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BU of 5o7p by Molmil
HER3 in complex with Fab MF3178
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MF3178 FAB heavy chain, MF3178 FAB light chain, ...
Authors:De Nardis, C, Gros, P.
Deposit date:2017-06-09
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade.
Cancer Cell, 33, 2018
5O2T
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BU of 5o2t by Molmil
Human KRAS in complex with darpin K27
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase KRas, MAGNESIUM ION, ...
Authors:Debreczeni, J.E, Guillard, S, Kolasinska-Zwierz, P, Breed, J, Zhang, J, Bery, N, Marwood, R, Tart, J, Stocki, P, Mistry, B, Phillips, C, Rabbitts, T, Jackson, R, Minter, R.
Deposit date:2017-05-22
Release date:2017-07-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange.
Nat Commun, 8, 2017
5O4E
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BU of 5o4e by Molmil
Crystal structure of VEGF in complex with heterodimeric Fcab JanusCT6
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Mlynek, G, Lobner, E, Kubinger, K, Humm, A, Obinger, C, Djinovic-Carugo, K.
Deposit date:2017-05-29
Release date:2017-08-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex.
MAbs, 9, 2017
5O19
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BU of 5o19 by Molmil
Japanese encephalitis virus non-structural protein 1 C-terminal domain
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Genome polyprotein, SULFATE ION
Authors:Poonsiri, T, Wright, G.S.A, Antonyuk, S.V.
Deposit date:2017-05-18
Release date:2018-01-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Study of the C-Terminal Domain of Nonstructural Protein 1 from Japanese Encephalitis Virus.
J. Virol., 92, 2018
5M33
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BU of 5m33 by Molmil
Structural tuning of CD81LEL (space group P21)
Descriptor: 1,2-ETHANEDIOL, CD81 antigen
Authors:Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G.
Deposit date:2016-10-14
Release date:2016-12-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017

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數據於2024-11-06公開中

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