3PGF
Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB)
Summary for 3PGF
Entry DOI | 10.2210/pdb3pgf/pdb |
Related PRD ID | PRD_900001 |
Descriptor | Maltose-binding periplasmic protein, SAB Heavy Chain, SAB Light Chain, ... (7 entities in total) |
Functional Keywords | maltodextrin binding protein, fab, antibody fragment, engineered binding protein, maltodextrin binding protein-de novo protein complex, maltodextrin binding protein/de novo protein |
Biological source | Escherichia coli More |
Cellular location | Periplasm: P0AEX9 Secreted : P0DOX5 |
Total number of polymer chains | 3 |
Total formula weight | 92840.60 |
Authors | Kossiakoff, A.A.,Duguid, E.M.,Sandstrom, A. (deposition date: 2010-11-01, release date: 2011-03-09, Last modification date: 2023-09-06) |
Primary citation | Rizk, S.S.,Paduch, M.,Heithaus, J.H.,Duguid, E.M.,Sandstrom, A.,Kossiakoff, A.A. Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins. Nat.Struct.Mol.Biol., 18:437-442, 2011 Cited by PubMed: 21378967DOI: 10.1038/nsmb.2002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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