Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7Y36
DownloadVisualize
BU of 7y36 by Molmil
Cryo-EM structure of the Teriparatide-bound human PTH1R-Gs complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, HYDROXIDE ION, ...
Authors:Zhai, X, Mao, C, Shen, Q, Zang, S, Shen, D, Zhang, H, Chen, Z, Wang, G, Zhang, C, Zhang, Y, Liu, Z.
Deposit date:2022-06-10
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of the Teriparatide-bound human PTH1R-Gs complex
to be published
7Y3G
DownloadVisualize
BU of 7y3g by Molmil
Cryo-EM structure of a class A orphan GPCR
Descriptor: G-protein coupled receptor 12, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Liu, Z.J, Hua, T, Li, H, Zhang, J.Y, Luo, F.
Deposit date:2022-06-10
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural insight into the constitutive activity of human orphan receptor GPR12.
Sci Bull (Beijing), 68, 2023
8DCS
DownloadVisualize
BU of 8dcs by Molmil
Cryo-EM structure of cyanopindolol-bound beta1-adrenergic receptor in complex with heterotrimeric Gs-protein
Descriptor: 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Endolysin,Endolysin,Beta-1 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Su, M, Paknejad, N, Hite, R.K, Huang, X.Y.
Deposit date:2022-06-17
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structures of beta 1 -adrenergic receptor in complex with Gs and ligands of different efficacies.
Nat Commun, 13, 2022
8DCR
DownloadVisualize
BU of 8dcr by Molmil
Cryo-EM structure of dobutamine-bound beta1-adrenergic receptor in complex with heterotrimeric Gs-protein
Descriptor: DOBUTAMINE, Endolysin,Endolysin,Beta-1 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Su, M, Paknejad, N, Hite, R.K, Huang, X.Y.
Deposit date:2022-06-17
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of beta 1 -adrenergic receptor in complex with Gs and ligands of different efficacies.
Nat Commun, 13, 2022
7Y65
DownloadVisualize
BU of 7y65 by Molmil
Cryo-EM structure of C5a peptide-bound C5aR1 in complex with Gi protein
Descriptor: C5a anaphylatoxin chemotactic receptor 1, C5apep peptide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Feng, Y.Y, Zhao, C, Yan, W, Shao, Z.H.
Deposit date:2022-06-18
Release date:2023-03-01
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of activation and biased signaling in complement receptor C5aR1.
Cell Res., 33, 2023
7Y64
DownloadVisualize
BU of 7y64 by Molmil
Cryo-EM structure of C5a-bound C5aR1 in complex with Gi protein
Descriptor: C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Feng, Y.Y, Zhao, C, Yan, W, Shao, Z.H.
Deposit date:2022-06-18
Release date:2023-03-01
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of activation and biased signaling in complement receptor C5aR1.
Cell Res., 33, 2023
7Y66
DownloadVisualize
BU of 7y66 by Molmil
Cryo-EM structure of BM213-bound C5aR1 in complex with Gi protein
Descriptor: BM213 peptide, C5a anaphylatoxin chemotactic receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Feng, Y.Y, Zhao, C, Yan, W, Shao, Z.H.
Deposit date:2022-06-18
Release date:2023-03-01
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Mechanism of activation and biased signaling in complement receptor C5aR1.
Cell Res., 33, 2023
7Y67
DownloadVisualize
BU of 7y67 by Molmil
Cryo-EM structure of C089-bound C5aR1(I116A) mutant in complex with Gi protein
Descriptor: C089 peptide, C5a anaphylatoxin chemotactic receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Feng, Y.Y, Zhao, C, Yan, W, Shao, Z.H.
Deposit date:2022-06-18
Release date:2023-03-01
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of activation and biased signaling in complement receptor C5aR1.
Cell Res., 33, 2023
7Y89
DownloadVisualize
BU of 7y89 by Molmil
Structure of the GPR17-Gi complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Ye, F, Chen, G.
Deposit date:2022-06-23
Release date:2022-10-12
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Cryo-EM structure of G-protein-coupled receptor GPR17 in complex with inhibitory G protein.
MedComm (2020), 3, 2022
7YAC
DownloadVisualize
BU of 7yac by Molmil
Paltusotine-bound SSTR2-Gi complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhao, J, Shao, Z.
Deposit date:2022-06-27
Release date:2023-04-19
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine.
Nat Commun, 14, 2023
7YAE
DownloadVisualize
BU of 7yae by Molmil
Octreotide-bound SSTR2-Gi complex
Descriptor: CHOLESTEROL, DPN-CYS-PHE-DTR-LYS-THR-CYS-THO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zhao, J, Shao, Z.
Deposit date:2022-06-28
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Prospect of acromegaly therapy: molecular mechanism of clinical drugs octreotide and paltusotine.
Nat Commun, 14, 2023
7YDP
DownloadVisualize
BU of 7ydp by Molmil
Cryo-EM structure of CD97/miniGs complex
Descriptor: Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:He, Y, Wang, N.
Deposit date:2022-07-04
Release date:2023-07-12
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of CD97 activation and G-protein coupling.
Cell Chem Biol, 30, 2023
7YDH
DownloadVisualize
BU of 7ydh by Molmil
Cryo EM structure of CD97/miniG13 complex
Descriptor: Adhesion G protein-coupled receptor E5 subunit beta, G protein subunit 13 (Gi2-mini-G13 chimera), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:He, Y, Wang, N.
Deposit date:2022-07-04
Release date:2023-07-12
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of CD97 activation and G-protein coupling.
Cell Chem Biol, 30, 2023
7YDM
DownloadVisualize
BU of 7ydm by Molmil
Cryo-EM structure of CD97/Gq complex
Descriptor: Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:He, Y, Wang, N.
Deposit date:2022-07-04
Release date:2023-07-12
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structural basis of CD97 activation and G-protein coupling.
Cell Chem Biol, 30, 2023
7YDJ
DownloadVisualize
BU of 7ydj by Molmil
Cryo EM structure of CD97/miniG12 complex
Descriptor: Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:He, Y, Wang, N.
Deposit date:2022-07-04
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Cryo EM structure of CD97/miniG12 complex
To Be Published
7YFC
DownloadVisualize
BU of 7yfc by Molmil
Cryo-EM structure of the histamine-bound histamine H4 receptor and Gq complex
Descriptor: CHOLESTEROL, Engineered G-alpha-q, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Im, D, Iwata, S, Asada, H.
Deposit date:2022-07-08
Release date:2023-10-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the agonists binding and receptor selectivity of human histamine H 4 receptor.
Nat Commun, 14, 2023
7YFD
DownloadVisualize
BU of 7yfd by Molmil
Cryo-EM structure of the imetit-bound histamine H4 receptor and Gq complex
Descriptor: 2-(1~{H}-imidazol-5-yl)ethyl carbamimidothioate, CHOLESTEROL, Engineered G-alpha-q, ...
Authors:Im, D, Iwata, S, Asada, H.
Deposit date:2022-07-08
Release date:2023-10-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the agonists binding and receptor selectivity of human histamine H 4 receptor.
Nat Commun, 14, 2023
7YJ4
DownloadVisualize
BU of 7yj4 by Molmil
Cryo-EM structure of the INSL5-bound human relaxin family peptidereceptor 4 (RXFP4)-Gi complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ...
Authors:Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Liu, H, Xu, H.E, Yang, D.H, Wang, M.W.
Deposit date:2022-07-19
Release date:2023-03-01
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Nat Commun, 14, 2023
7YK6
DownloadVisualize
BU of 7yk6 by Molmil
Cryo-EM structure of the compound 4-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex
Descriptor: 1-[2-(4-chlorophenyl)ethyl]-3-[(7-ethyl-5-oxidanyl-1H-indol-3-yl)methylideneamino]guanidine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Liu, H, Xu, H.E, Yang, D.H, Wang, M.W.
Deposit date:2022-07-21
Release date:2023-03-01
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Nat Commun, 14, 2023
7YK7
DownloadVisualize
BU of 7yk7 by Molmil
Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ...
Authors:Chen, Y, Zhou, Q.T, Wang, J, Xu, Y.W, Wang, Y, Yan, J.H, Wang, Y.B, Zhu, Q, Zhao, F.H, Li, C.H, Chen, C.W, Cai, X.Q, Bathgate, R.A.D, Shen, C, Xu, H.E, Yang, D.H, Liu, H, Wang, M.W.
Deposit date:2022-07-21
Release date:2023-03-01
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).
Nat Commun, 14, 2023
7YKD
DownloadVisualize
BU of 7ykd by Molmil
Cryo-EM structure of the human chemerin receptor 1 complex with the C-terminal nonapeptide of chemerin
Descriptor: CHOLESTEROL, Chemerin-like receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Chen, G, Liao, Q, Ye, R.D, Wang, J.
Deposit date:2022-07-22
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Cryo-EM structure of the human chemerin receptor 1-Gi protein complex bound to the C-terminal nonapeptide of chemerin.
Proc.Natl.Acad.Sci.USA, 120, 2023
7YOO
DownloadVisualize
BU of 7yoo by Molmil
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Kang, H, Park, C, Kim, J, Choi, H.-J.
Deposit date:2022-08-01
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling.
Structure, 31, 2023
7YON
DownloadVisualize
BU of 7yon by Molmil
Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Kang, H, Park, C, Kim, J, Choi, H.-J.
Deposit date:2022-08-01
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling.
Structure, 31, 2023
7YP7
DownloadVisualize
BU of 7yp7 by Molmil
apo-ADGRG2 coupled to Gs
Descriptor: Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Liu, Z.M, Bu, R.Q, Xue, C.Y, Guo, S.C, Yuan, D.P, Xiao, P, Sun, J.P.
Deposit date:2022-08-02
Release date:2022-08-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:apo-ADGRG2 coupled to Gs
Nat.Chem.Biol., 2022
8DZS
DownloadVisualize
BU of 8dzs by Molmil
GR89,696 bound Kappa Opioid Receptor in complex with Gz
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(z) subunit alpha, ...
Authors:Fay, J.F, Che, T.
Deposit date:2022-08-08
Release date:2023-05-03
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Ligand and G-protein selectivity in the kappa-opioid receptor.
Nature, 617, 2023

221051

數據於2024-06-12公開中

PDB statisticsPDBj update infoContact PDBjnumon