7Y3G

Cryo-EM structure of a class A orphan GPCR

Summary for 7Y3G

Entry DOI	10.2210/pdb7y3g/pdb
EMDB information	33594
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total)
Functional Keywords	orphan g protein coupled-receptor, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	150075.79
Authors	Liu, Z.J.,Hua, T.,Li, H.,Zhang, J.Y.,Luo, F. (deposition date: 2022-06-10, release date: 2023-06-07)
Primary citation	Li, H.,Zhang, J.,Yu, Y.,Luo, F.,Wu, L.,Liu, J.,Chen, N.,Liu, Z.,Hua, T. Structural insight into the constitutive activity of human orphan receptor GPR12. Sci Bull (Beijing), 68:95-104, 2023 Cited by PubMed: 36593162 DOI: 10.1016/j.scib.2022.12.023 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.77 Å)

Structure validation