7YK7

Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex

Summary for 7YK7

Entry DOI	10.2210/pdb7yk7/pdb
EMDB information	33889
Descriptor	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(i) subunit alpha-2, Relaxin-3 receptor 2, ... (6 entities in total)
Functional Keywords	human relaxin family peptide receptor 4, g protein-coupled receptor, ligand recognition, structural protein
Biological source	Bos taurus (Bovine) More
Total number of polymer chains	5
Total formula weight	154358.86
Authors	Chen, Y.,Zhou, Q.T.,Wang, J.,Xu, Y.W.,Wang, Y.,Yan, J.H.,Wang, Y.B.,Zhu, Q.,Zhao, F.H.,Li, C.H.,Chen, C.W.,Cai, X.Q.,Bathgate, R.A.D.,Shen, C.,Xu, H.E.,Yang, D.H.,Liu, H.,Wang, M.W. (deposition date: 2022-07-21, release date: 2023-03-01)
Primary citation	Chen, Y.,Zhou, Q.,Wang, J.,Xu, Y.,Wang, Y.,Yan, J.,Wang, Y.,Zhu, Q.,Zhao, F.,Li, C.,Chen, C.W.,Cai, X.,Bathgate, R.A.D.,Shen, C.,Eric Xu, H.,Yang, D.,Liu, H.,Wang, M.W. Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4). Nat Commun, 14:492-492, 2023 Cited by PubMed: 36717591 DOI: 10.1038/s41467-023-36182-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.75 Å)

Structure validation