7YFC

Cryo-EM structure of the histamine-bound histamine H4 receptor and Gq complex

Summary for 7YFC

Entry DOI	10.2210/pdb7yfc/pdb
EMDB information	33785
Descriptor	Engineered G-alpha-q, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFv16, ... (8 entities in total)
Functional Keywords	gpcr, aminergic receptor, histamine receptor, membrane protein
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	196304.72
Authors	Im, D.,Iwata, S.,Asada, H. (deposition date: 2022-07-08, release date: 2023-10-25, Last modification date: 2023-11-22)
Primary citation	Im, D.,Kishikawa, J.I.,Shiimura, Y.,Hisano, H.,Ito, A.,Fujita-Fujiharu, Y.,Sugita, Y.,Noda, T.,Kato, T.,Asada, H.,Iwata, S. Structural insights into the agonists binding and receptor selectivity of human histamine H4 receptor. Nat Commun, 14:6538-, 2023 Cited by DOI: 10.1038/s41467-023-42260-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation