7YJ4
Cryo-EM structure of the INSL5-bound human relaxin family peptidereceptor 4 (RXFP4)-Gi complex
Summary for 7YJ4
Entry DOI | 10.2210/pdb7yj4/pdb |
EMDB information | 33871 |
Descriptor | Insulin-like peptide INSL5 A chain, Insulin-like peptide INSL5 B chain, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | human relaxin family peptide receptor 4, g protein-coupled receptor, ligand recognition, structural protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 158937.16 |
Authors | Chen, Y.,Zhou, Q.T.,Wang, J.,Xu, Y.W.,Wang, Y.,Yan, J.H.,Wang, Y.B.,Zhu, Q.,Zhao, F.H.,Li, C.H.,Chen, C.W.,Cai, X.Q.,Bathgate, R.A.D.,Shen, C.,Liu, H.,Xu, H.E.,Yang, D.H.,Wang, M.W. (deposition date: 2022-07-19, release date: 2023-03-01) |
Primary citation | Chen, Y.,Zhou, Q.,Wang, J.,Xu, Y.,Wang, Y.,Yan, J.,Wang, Y.,Zhu, Q.,Zhao, F.,Li, C.,Chen, C.W.,Cai, X.,Bathgate, R.A.D.,Shen, C.,Eric Xu, H.,Yang, D.,Liu, H.,Wang, M.W. Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4). Nat Commun, 14:492-492, 2023 Cited by PubMed: 36717591DOI: 10.1038/s41467-023-36182-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.19 Å) |
Structure validation
Download full validation report