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8THZ
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BU of 8thz by Molmil
CryoEM structure of neutralizing antibodies CBH-7 and HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CBH-7 Heavy chain, ...
Authors:Shahid, S, Jiang, L, Liu, Y, Hasan, S.S, Mariuzza, R.A.
Deposit date:2023-07-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:CryoEM structure of neutralizing antibodies CBH-7 and HC84.26 in complex with Hepatitis C virus envelope glycoprotein E2
To Be Published
8UDG
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BU of 8udg by Molmil
S1V2-72 Fab bound to EHA2 from influenza B/Malaysia/2506/2004
Descriptor: Hemagglutinin, S1V2-72 heavy chain, S1V2-72 light chain
Authors:Finney, J, Kong, S, Walsh Jr, R.M, Harrison, S.C, Kelsoe, G.
Deposit date:2023-09-28
Release date:2023-11-15
Last modified:2024-01-10
Method:ELECTRON MICROSCOPY (4.98 Å)
Cite:Protective human antibodies against a conserved epitope in pre- and postfusion influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 121, 2024
6VYO
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BU of 6vyo by Molmil
Crystal structure of RNA binding domain of nucleocapsid phosphoprotein from SARS coronavirus 2
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ...
Authors:Chang, C, Michalska, K, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Kim, Y, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-02-27
Release date:2020-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
6WKP
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BU of 6wkp by Molmil
Crystal structure of RNA-binding domain of nucleocapsid phosphoprotein from SARS CoV-2, monoclinic crystal form
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoprotein, ZINC ION
Authors:Chang, C, Michalska, K, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Kim, Y, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-16
Release date:2020-04-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
7SL5
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BU of 7sl5 by Molmil
Crystal Structure of VP12E7 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor: Heavy chain VP12E7 Fab, Light chain VP12E7 Fab, PRO-SER-LYS-ARG-SER-PHE-ILE-GLU-ASP-LEU-LEU-PHE-ASN
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-10-22
Release date:2022-07-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7SKZ
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BU of 7skz by Molmil
Crystal Structure of VN01H1 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor: Heavy chain of VN01H1 Fab, Light chain of VN01H1 Fab, PRO-SER-LYS-ARG-SER-PHE-ILE-GLU-ASP-LEU-LEU-PHE-ASN
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-10-22
Release date:2022-07-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7U0A
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BU of 7u0a by Molmil
Crystal Structure of C77G12 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor: CHLORIDE ION, Heavy chain Fab C77G12, Light chain Fab C77G12, ...
Authors:Tortorici, M.A, Veesler, D.
Deposit date:2022-02-17
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7U0E
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BU of 7u0e by Molmil
Crystal Structure of C13C9 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor: Heavy chain Fab C13C9, Light chain Fab C13C9, SARS-CoV-2 S fusion peptide
Authors:Tortorici, M.A, Veesler, D.
Deposit date:2022-02-18
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7U09
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BU of 7u09 by Molmil
Crystal Structure of C13B8 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor: Heavy chain Fab C13B8, Light chain Fab C13B8, SARS-CoV-2 S fusion peptide
Authors:Tortorici, M.A, Veesler, D.
Deposit date:2022-02-17
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7K7Y
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BU of 7k7y by Molmil
Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E9
Descriptor: Botulinum neurotoxin type E, JLE-E9
Authors:Lam, K, Jin, R.
Deposit date:2020-09-24
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells.
Toxins, 12, 2020
7K84
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BU of 7k84 by Molmil
Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E5
Descriptor: Botulinum neurotoxin type E, JLE-E5, SULFATE ION, ...
Authors:Lam, K, Jin, R.
Deposit date:2020-09-25
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells.
Toxins, 12, 2020
7M1H
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BU of 7m1h by Molmil
Crystal structure of LC/A-JPU-C10-JPU-D12-JPU-B8-JPU-G3-ciA-F12-ciA-D12
Descriptor: Botulinum neurotoxin A light chain, JPU-B8, JPU-C10, ...
Authors:Lam, K, Jin, R.
Deposit date:2021-03-13
Release date:2021-12-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
Plos Pathog., 18, 2022
7YKJ
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BU of 7ykj by Molmil
Omicron RBDs bound with P3E6 Fab (one up and one down)
Descriptor: P3E6 heavy chain, P3E6 light chain, Spike glycoprotein
Authors:Tang, B, Dang, S.
Deposit date:2022-07-22
Release date:2022-12-28
Last modified:2023-01-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2.
Emerg Microbes Infect, 12, 2023
1HQ4
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BU of 1hq4 by Molmil
STRUCTURE OF NATIVE CATALYTIC ANTIBODY HA5-19A4
Descriptor: ANTIBODY HA5-19A4 FAB HEAVY CHAIN, ANTIBODY HA5-19A4 FAB LIGHT CHAIN, CADMIUM ION
Authors:Paschall, C.M, Hasserodt, J, Lerner, R.A, Janda, K.D, Christianson, D.W.
Deposit date:2000-12-14
Release date:2003-06-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Polyene Cyclization Reactions
Thesis, 2000
1I3V
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BU of 1i3v by Molmil
THREE-DIMENSIONAL STRUCTURE OF A LAMA VHH DOMAIN UNLIGANDED
Descriptor: ANTIBODY VHH LAMA DOMAIN
Authors:Spinelli, S, Tegoni, M, Frenken, L, van Vliet, C, Cambillau, C.
Deposit date:2001-02-16
Release date:2001-08-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Lateral recognition of a dye hapten by a llama VHH domain.
J.Mol.Biol., 311, 2001
6SXI
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BU of 6sxi by Molmil
Antibody-anti-idiotype complex: AP33 Fab (hepatitis C virus E2 antibody) - B2.1A scFv (anti-idiotype)
Descriptor: Fab heavy chain, Fab light chain, GLYCEROL, ...
Authors:Taylor, G.L, Potter, J.A, Fadda, V, Patel, A.H, Owsianka, A.M, Cowtan, V.M.
Deposit date:2019-09-26
Release date:2020-10-07
Last modified:2021-01-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design.
NPJ Vaccines, 6, 2021
4ZD3
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BU of 4zd3 by Molmil
Structure of a transglutaminase 2-specific autoantibody Fab fragment
Descriptor: 679-14-14E06 Fab fragment heavy chain, 679-14-14E06 Fab fragment light chain
Authors:Chen, X, Dalhus, B, Hnida, K, Iversen, R, Sollid, L.M.
Deposit date:2015-04-16
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease.
J.Biol.Chem., 290, 2015
1UWX
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BU of 1uwx by Molmil
P1.2 serosubtype antigen derived from N. meningitidis PorA in complex with Fab fragment
Descriptor: ANTIBODY, CLASS 1 OUTER MEMBRANE PROTEIN VARIABLE REGION 2, PROTEIN G-PRIME
Authors:Tzitzilonis, C, Prince, S.M, Collins, R.F, Maiden, M.C.J, Feavers, I.M, Derrick, J.P.
Deposit date:2004-02-12
Release date:2005-06-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Variation and Immune Recognition of the P1.2 Subtype Meningococcal Antigen.
Proteins: Struct., Funct., Bioinf., 62, 2005
1P7K
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BU of 1p7k by Molmil
Crystal structure of an anti-ssDNA antigen-binding fragment (Fab) bound to 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid (HEPES)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Schuermann, J.P, Henzl, M.T, Deutscher, S.L, Tanner, J.J.
Deposit date:2003-05-02
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of an anti-DNA fab complexed with a non-DNA ligand provides insights into cross-reactivity and molecular mimicry.
Proteins, 57, 2004
5FHX
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BU of 5fhx by Molmil
CRYSTAL STRUCTURE OF CODV IN COMPLEX WITH IL4 AT 2.55 Ang. RESOLUTION.
Descriptor: Antibody fragment light chain, Interleukin-4, PHOSPHATE ION, ...
Authors:Vallee, F, Dupuy, A, Rak, A.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications.
Mabs, 8, 2016
6MG7
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BU of 6mg7 by Molmil
Crystal structure of the RV144 C1-C2 specific antibody CH54 Fab in complex with HIV-1 CLADE A/E GP120 and M48U1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CH54 Fab heavy chain, CH54 Fab light chain, ...
Authors:Van, V, Tolbert, W.D, Pazgier, M.
Deposit date:2018-09-13
Release date:2019-09-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.
Mbio, 11, 2020
6OFI
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BU of 6ofi by Molmil
CRYSTAL STRUCTURE OF the RV144 C1-C2 SPECIFIC ANTIBODY CH55 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CH55 Fab heavy chain, CH55 Fab light chain, ...
Authors:Tolbert, W.D, Yan, F, Van, V, Pazgier, M.
Deposit date:2019-03-29
Release date:2020-06-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.
Mbio, 11, 2020
6OED
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BU of 6oed by Molmil
CRYSTAL STRUCTURE OF THE RV144 C1-C2 SPECIFIC ANTIBODY CH55 FAB
Descriptor: CH55 Fab heavy chain, CH55 Fab light chain
Authors:Yan, F, Van, V, Tolbert, W.D, Pazgier, M.
Deposit date:2019-03-27
Release date:2020-07-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.461 Å)
Cite:Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.
Mbio, 11, 2020
6OEJ
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BU of 6oej by Molmil
CRYSTAL STRUCTURE OF THE NON-NEUTRALIZING AND ADCC-POTENT ANTIBODY C11 IN COMPLEX WITH HIV-1 CLADE A/E GP120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C11 Fab heavy chain, C11 Fab light chain, ...
Authors:Tolbert, W.D, Pazgier, M.
Deposit date:2019-03-27
Release date:2020-07-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.
Mbio, 11, 2020
1PSK
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BU of 1psk by Molmil
THE CRYSTAL STRUCTURE OF AN FAB FRAGMENT THAT BINDS TO THE MELANOMA-ASSOCIATED GD2 GANGLIOSIDE
Descriptor: ANTIBODY
Authors:Pichla, S.L, Murali, R, Burnett, R.M.
Deposit date:1997-03-03
Release date:1997-09-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of a Fab fragment to the melanoma-associated GD2 ganglioside.
J.Struct.Biol., 119, 1997

224572

數據於2024-09-04公開中

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