6SXI
Antibody-anti-idiotype complex: AP33 Fab (hepatitis C virus E2 antibody) - B2.1A scFv (anti-idiotype)
Summary for 6SXI
Entry DOI | 10.2210/pdb6sxi/pdb |
Descriptor | Fab heavy chain, Fab light chain, Single chain Fv - heavy chain, ... (6 entities in total) |
Functional Keywords | anti-idiotype, antigen binding fragment, single chain fv, complex, immune system |
Biological source | Mus musculus (House mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 72829.76 |
Authors | Taylor, G.L.,Potter, J.A.,Fadda, V.,Patel, A.H.,Owsianka, A.M.,Cowtan, V.M. (deposition date: 2019-09-26, release date: 2020-10-07, Last modification date: 2021-01-20) |
Primary citation | Cowton, V.M.,Owsianka, A.M.,Fadda, V.,Ortega-Prieto, A.M.,Cole, S.J.,Potter, J.A.,Skelton, J.K.,Jeffrey, N.,Di Lorenzo, C.,Dorner, M.,Taylor, G.L.,Patel, A.H. Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design. NPJ Vaccines, 6:7-7, 2021 Cited by PubMed: 33420102DOI: 10.1038/s41541-020-00269-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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