6SXI

Antibody-anti-idiotype complex: AP33 Fab (hepatitis C virus E2 antibody) - B2.1A scFv (anti-idiotype)

Summary for 6SXI

• Entry DOI: 10.2210/pdb6sxi/pdb
• Descriptor: Fab heavy chain, Fab light chain, Single chain Fv - heavy chain, ... (6 entities in total)
• Functional Keywords: anti-idiotype, antigen binding fragment, single chain fv, complex, immune system
• Biological source: Mus musculus (House mouse); More
• Total number of polymer chains: 4
• Total formula weight: 72829.76

Authors

Taylor, G.L.,Potter, J.A.,Fadda, V.,Patel, A.H.,Owsianka, A.M.,Cowtan, V.M. (deposition date: 2019-09-26, release date: 2020-10-07, Last modification date: 2021-01-20)

• Primary citation: Cowton, V.M.,Owsianka, A.M.,Fadda, V.,Ortega-Prieto, A.M.,Cole, S.J.,Potter, J.A.,Skelton, J.K.,Jeffrey, N.,Di Lorenzo, C.,Dorner, M.,Taylor, G.L.,Patel, A.H.; Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design.; NPJ Vaccines, 6:7-7, 2021; PubMed: 33420102; DOI: 10.1038/s41541-020-00269-1

Experimental method

X-RAY DIFFRACTION (1.85 Å)