6OEJ

CRYSTAL STRUCTURE OF THE NON-NEUTRALIZING AND ADCC-POTENT ANTIBODY C11 IN COMPLEX WITH HIV-1 CLADE A/E GP120

Summary for 6OEJ

• Entry DOI: 10.2210/pdb6oej/pdb
• Related: 4FZ8
• Descriptor: clade A/E 93TH057 HIV-1 gp120 core, C11 Fab heavy chain, C11 Fab light chain, ... (5 entities in total)
• Functional Keywords: hiv-1 gp120, clade a/e 93th057, viral protein, viral protein-immune system complex, immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 190743.67

Authors

Tolbert, W.D.,Pazgier, M. (deposition date: 2019-03-27, release date: 2020-07-15, Last modification date: 2023-10-11)

• Primary citation: Tolbert, W.D.,Van, V.,Sherburn, R.,Tuyishime, M.,Yan, F.,Nguyen, D.N.,Stanfield-Oakley, S.,Easterhoff, D.,Bonsignori, M.,Haynes, B.F.,Moody, M.A.,Ray, K.,Ferrari, G.,Lewis, G.K.,Pazgier, M.; Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.; Mbio, 11:-, 2020; PubMed: 32605979; DOI: 10.1128/mBio.00208-20

Experimental method

X-RAY DIFFRACTION (3.45 Å)