4FZ8
Crystal structure of C11 Fab, an ADCC mediating anti-HIV-1 antibody.
Summary for 4FZ8
Entry DOI | 10.2210/pdb4fz8/pdb |
Related | 3TNM 3TNN 4FZE |
Descriptor | FAB heavy chain of human ANTI-HIV-1 ENV ANTIBODY C11, FAB light chain of human ANTI-HIV-1 ENV ANTIBODY C11, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | adcc, anti-hiv-1 env antibody c11, cd4i antibody, fab, viral glycoprotein gp120, hiv-1 env, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 49400.45 |
Authors | Wu, X.,Tolbert, W.D.,Pazgier, M. (deposition date: 2012-07-06, release date: 2013-07-10, Last modification date: 2023-09-13) |
Primary citation | Tolbert, W.D.,Van, V.,Sherburn, R.,Tuyishime, M.,Yan, F.,Nguyen, D.N.,Stanfield-Oakley, S.,Easterhoff, D.,Bonsignori, M.,Haynes, B.F.,Moody, M.A.,Ray, K.,Ferrari, G.,Lewis, G.K.,Pazgier, M. Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial. Mbio, 11:-, 2020 Cited by PubMed: 32605979DOI: 10.1128/mBio.00208-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
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