4ZD3

Structure of a transglutaminase 2-specific autoantibody Fab fragment

Summary for 4ZD3

• Entry DOI: 10.2210/pdb4zd3/pdb
• Descriptor: 679-14-14E06 Fab fragment heavy chain, 679-14-14E06 Fab fragment light chain (3 entities in total)
• Functional Keywords: transglutaminase 2, antibody, fab fragment, celiac disease, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 47701.17

Authors

Chen, X.,Dalhus, B.,Hnida, K.,Iversen, R.,Sollid, L.M. (deposition date: 2015-04-16, release date: 2015-07-22, Last modification date: 2024-01-10)

• Primary citation: Chen, X.,Hnida, K.,Graewert, M.A.,Andersen, J.T.,Iversen, R.,Tuukkanen, A.,Svergun, D.,Sollid, L.M.; Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease.; J.Biol.Chem., 290:21365-21375, 2015; PubMed: 26160175; DOI: 10.1074/jbc.M115.669895

Experimental method

X-RAY DIFFRACTION (2.4 Å)