5FHX

CRYSTAL STRUCTURE OF CODV IN COMPLEX WITH IL4 AT 2.55 Ang. RESOLUTION.

Summary for 5FHX

• Entry DOI: 10.2210/pdb5fhx/pdb
• Descriptor: Interleukin-4, antibody fragment heavy-chain, Antibody fragment light chain, ... (5 entities in total)
• Functional Keywords: cross-over dual variable immunoglobulin multifunctional biotherapeutic drug, codv, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 88028.23

Authors

Vallee, F.,Dupuy, A.,Rak, A. (deposition date: 2015-12-22, release date: 2016-03-30, Last modification date: 2018-10-24)

• Primary citation: Steinmetz, A.,Vallee, F.,Beil, C.,Lange, C.,Baurin, N.,Beninga, J.,Capdevila, C.,Corvey, C.,Dupuy, A.,Ferrari, P.,Rak, A.,Wonerow, P.,Kruip, J.,Mikol, V.,Rao, E.; CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications.; Mabs, 8:867-878, 2016; PubMed: 26984268; DOI: 10.1080/19420862.2016.1162932

Experimental method

X-RAY DIFFRACTION (2.55 Å)