6WKP

Crystal structure of RNA-binding domain of nucleocapsid phosphoprotein from SARS CoV-2, monoclinic crystal form

Summary for 6WKP

Entry DOI	10.2210/pdb6wkp/pdb
Descriptor	Nucleoprotein, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	csgid, covid-19, sars cov-2, rna-binding domain, nucleocapsid protein, nucleoprotein, structural genomics, center for structural genomics of infectious diseases, viral protein, rna binding protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains	4
Total formula weight	57063.23
Authors	Chang, C.,Michalska, K.,Jedrzejczak, R.,Maltseva, N.,Endres, M.,Godzik, A.,Kim, Y.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-04-16, release date: 2020-04-29, Last modification date: 2024-02-28)
Primary citation	Kim, Y.,Maltseva, N.,Tesar, C.,Jedrzejczak, R.,Endres, M.,Ma, H.,Dugan, H.L.,Stamper, C.T.,Chang, C.,Li, L.,Changrob, S.,Zheng, N.Y.,Huang, M.,Ramanathan, A.,Wilson, P.,Michalska, K.,Joachimiak, A. Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies. Iscience, 27:108976-108976, 2024 Cited by PubMed: 38327783 DOI: 10.1016/j.isci.2024.108976 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.67 Å)

Structure validation