8SEL
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8F9Z
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![BU of 8f9z by Molmil](/molmil-images/mine/8f9z) | Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-14204, an HIV-1 gp120 antagonist | Descriptor: | (5M)-N-{(1S)-2-amino-1-[5-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl}-5-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrole-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Kwon, Y.D, Kwong, P.D. | Deposit date: | 2022-11-25 | Release date: | 2023-01-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists. Int J Mol Sci, 23, 2022
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8RTH
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![BU of 8rth by Molmil](/molmil-images/mine/8rth) | Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase | Descriptor: | 3-methylcrotonyl-CoA carboxylase, putative, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ... | Authors: | Ruiz, F.M, Plaza-Pegueroles, A, Fernandez-Tornero, C. | Deposit date: | 2024-01-26 | Release date: | 2024-04-17 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.37 Å) | Cite: | The cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase provides mechanistic and dynamic insights into its enzymatic function. Structure, 32, 2024
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8FA0
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4LWA
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![BU of 4lwa by Molmil](/molmil-images/mine/4lwa) | Structure of Bacillus subtilis nitric oxide synthase in complex with ((2S, 3S)-1,3-bis((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methoxy)-2-aminobutane | Descriptor: | 6,6'-{[(2S,3S)-2-aminobutane-1,3-diyl]bis(oxymethanediyl)}bis(4-methylpyridin-2-amine), CHLORIDE ION, GLYCEROL, ... | Authors: | Holden, J.K, Li, H, Poulos, T.P. | Deposit date: | 2013-07-26 | Release date: | 2013-10-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural and biological studies on bacterial nitric oxide synthase inhibitors. Proc.Natl.Acad.Sci.USA, 110, 2013
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8F8Y
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![BU of 8f8y by Molmil](/molmil-images/mine/8f8y) | PHF2 (PHD+JMJ) in Complex with VRK1 N-Terminal Peptide | Descriptor: | 1,2-ETHANEDIOL, Lysine-specific demethylase PHF2, SULFATE ION, ... | Authors: | Horton, J.R, Cheng, X. | Deposit date: | 2022-11-22 | Release date: | 2023-01-18 | Last modified: | 2023-02-08 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2. J.Biol.Chem., 299, 2022
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4MHV
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![BU of 4mhv by Molmil](/molmil-images/mine/4mhv) | Crystal structure of the PNT domain of human ETS2 | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Newman, J.A, Cooper, C.D.O, Krojer, T, Shrestha, L, Burgess-brown, N, Arrowsmith, C.H, Bountra, C, Edwards, A, Gileadi, O. | Deposit date: | 2013-08-30 | Release date: | 2013-09-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of the PNT domain of human ETS2 To be Published
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7O7A
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6EKC
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![BU of 6ekc by Molmil](/molmil-images/mine/6ekc) | Crystal structure of the BSD2 homolog of Arabidopsis thaliana bound to the octameric assembly of RbcL from Thermosynechococcus elongatus | Descriptor: | DnaJ/Hsp40 cysteine-rich domain superfamily protein, Ribulose bisphosphate carboxylase large chain, ZINC ION | Authors: | Aigner, H, Wilson, R.H, Bracher, A, Calisse, L, Bhat, J.Y, Hartl, F.U, Hayer-Hartl, M. | Deposit date: | 2017-09-26 | Release date: | 2017-12-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Plant RuBisCo assembly in E. coli with five chloroplast chaperones including BSD2. Science, 358, 2017
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8S7C
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![BU of 8s7c by Molmil](/molmil-images/mine/8s7c) | Ternary Complex of Cachd1, FZD5 and LRP6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-5, ... | Authors: | Zhao, Y, Ren, J, Jones, E.Y. | Deposit date: | 2024-02-29 | Release date: | 2024-04-24 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (4.7 Å) | Cite: | Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain. Science, 384, 2024
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4LX9
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6ET6
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![BU of 6et6 by Molmil](/molmil-images/mine/6et6) | Crystal structure of muramidase from Acinetobacter baumannii AB 5075UW prophage | Descriptor: | GLYCEROL, Lysozyme, SULFATE ION | Authors: | Boyko, K.M, Nikolaeva, A.Y, Sykilinda, N.N, Shneider, M.M, Miroshnikov, K.A, Popov, V.O. | Deposit date: | 2017-10-25 | Release date: | 2018-09-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure of anAcinetobacterBroad-Range Prophage Endolysin Reveals a C-Terminal alpha-Helix with the Proposed Role in Activity against Live Bacterial Cells. Viruses, 10, 2018
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6ET8
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![BU of 6et8 by Molmil](/molmil-images/mine/6et8) | Crystal structure of AlbA in complex with albicidin | Descriptor: | Albicidin resistance protein, SULFATE ION, albicidin | Authors: | Driller, R, Rostock, L, Alings, C, Graetz, S, Suessmuth, R, Mainz, A, Wahl, M.C, Loll, B. | Deposit date: | 2017-10-25 | Release date: | 2018-08-15 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular insights into antibiotic resistance - how a binding protein traps albicidin. Nat Commun, 9, 2018
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8F8Z
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6ETJ
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![BU of 6etj by Molmil](/molmil-images/mine/6etj) | HUMAN PFKFB3 IN COMPLEX WITH KAN0438241 | Descriptor: | 4-[[3-(5-fluoranyl-2-oxidanyl-phenyl)phenyl]sulfonylamino]-2-oxidanyl-benzoic acid, 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, ... | Authors: | Gustafsson, N.M.S, Lundback, T, Farnegardh, K, Groth, P, Wiitta, E, Jonsson, M, Hallberg, K, Pennisi, R, Huguet Ninou, A, Martinsson, J, Norstrom, C, Schultz, J, Andersson, M, Markova, N, Marttila, P, Norin, M, Olin, T, Helleday, T. | Deposit date: | 2017-10-26 | Release date: | 2018-11-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun, 9, 2018
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4LYI
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![BU of 4lyi by Molmil](/molmil-images/mine/4lyi) | Crystal Structure of apo-BRD4(1) | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, IODIDE ION, ... | Authors: | Wohlwend, D. | Deposit date: | 2013-07-31 | Release date: | 2014-01-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew.Chem.Int.Ed.Engl., 52, 2013
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8S5M
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8FMA
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![BU of 8fma by Molmil](/molmil-images/mine/8fma) | Nodavirus RNA replication proto-crown, detergent-solubliized C11 multimer | Descriptor: | RNA-directed RNA polymerase | Authors: | Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P. | Deposit date: | 2022-12-22 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching. Proc.Natl.Acad.Sci.USA, 120, 2023
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7O4Y
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8FQ4
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![BU of 8fq4 by Molmil](/molmil-images/mine/8fq4) | AAV1 VP3 Only Capsid | Descriptor: | Capsid protein | Authors: | Mietzsch, M, McKenna, R. | Deposit date: | 2023-01-05 | Release date: | 2023-02-08 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.27 Å) | Cite: | Production and characterization of an AAV1-VP3-only capsid: An analytical benchmark standard. Mol Ther Methods Clin Dev, 29, 2023
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7NWF
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![BU of 7nwf by Molmil](/molmil-images/mine/7nwf) | Crystal structure of Bacteroides thetaiotamicron EndoBT-3987 in complex with hybrid-type glycan (GalGlcNAcMan5GlcNAc) product | Descriptor: | Endo-beta-N-acetylglucosaminidase F1, GLYCEROL, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Trastoy, B, Du, J.J, Garcia-Alija, M, Sundberg, E.J, Guerin, M.E. | Deposit date: | 2021-03-16 | Release date: | 2021-08-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | GH18 endo-beta-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans. J.Biol.Chem., 297, 2021
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7NQ4
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8FM9
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![BU of 8fm9 by Molmil](/molmil-images/mine/8fm9) | Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer | Descriptor: | RNA-directed RNA polymerase | Authors: | Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P. | Deposit date: | 2022-12-22 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching. Proc.Natl.Acad.Sci.USA, 120, 2023
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6EWQ
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![BU of 6ewq by Molmil](/molmil-images/mine/6ewq) | Putative sugar aminotransferase Spr1654 from Streptococcus pneumoniae, PLP-form | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Putative capsular polysaccharide biosynthesis protein | Authors: | Achour, A, Sun, R, Sandalova, T, Han, X. | Deposit date: | 2017-11-06 | Release date: | 2018-05-02 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis inStreptococcus pneumoniae. Open Biol, 8, 2018
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6F2A
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![BU of 6f2a by Molmil](/molmil-images/mine/6f2a) | Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/Lysine | Descriptor: | ACETIC ACID, CHLORIDE ION, FE (II) ION, ... | Authors: | Isabet, T, Stura, E.A, Legrand, P, Zaparucha, A, Bastard, K. | Deposit date: | 2017-11-24 | Release date: | 2018-11-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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