8S7C

Ternary Complex of Cachd1, FZD5 and LRP6

Summary for 8S7C

Entry DOI	10.2210/pdb8s7c/pdb
Descriptor	VWFA and cache domain-containing protein 1, Frizzled-5, Low-density lipoprotein receptor-related protein 6, ... (5 entities in total)
Functional Keywords	cachd1 frizzled-5 lrp6, signaling protein
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	9
Total formula weight	637942.28
Authors	Zhao, Y.,Ren, J.,Jones, E.Y. (deposition date: 2024-02-29, release date: 2024-04-24, Last modification date: 2024-05-15)
Primary citation	Powell, G.T.,Faro, A.,Zhao, Y.,Stickney, H.,Novellasdemunt, L.,Henriques, P.,Gestri, G.,Redhouse White, E.,Ren, J.,Lu, W.,Young, R.M.,Hawkins, T.A.,Cavodeassi, F.,Schwarz, Q.,Dreosti, E.,Raible, D.W.,Li, V.S.W.,Wright, G.J.,Jones, E.Y.,Wilson, S.W. Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain. Science, 384:573-579, 2024 Cited by PubMed: 38696577 DOI: 10.1126/science.ade6970 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.7 Å)

Structure validation