8RTH

Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase

Summary for 8RTH

Entry DOI	10.2210/pdb8rth/pdb
EMDB information	19492
Descriptor	3-methylcrotonyl-CoA carboxylase, putative, methylcrotonoyl-CoA carboxylase, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL (3 entities in total)
Functional Keywords	carboxylase, trypanosoma brucei, biosynthetic protein, transferase
Biological source	Trypanosoma brucei More
Total number of polymer chains	12
Total formula weight	844979.57
Authors	Ruiz, F.M.,Plaza-Pegueroles, A.,Fernandez-Tornero, C. (deposition date: 2024-01-26, release date: 2024-04-17, Last modification date: 2024-07-24)
Primary citation	Plaza-Pegueroles, A.,Aphasizheva, I.,Aphasizhev, R.,Fernandez-Tornero, C.,Ruiz, F.M. The cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase provides mechanistic and dynamic insights into its enzymatic function. Structure, 32:930-, 2024 Cited by PubMed: 38593794 DOI: 10.1016/j.str.2024.03.010 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.37 Å)

Structure validation