8RTH

Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005929	cellular_component	cilium
A	0009374	molecular_function	biotin binding
A	0016874	molecular_function	ligase activity
A	0019856	biological_process	pyrimidine nucleobase biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
B	0005739	cellular_component	mitochondrion
B	0006552	biological_process	L-leucine catabolic process
B	0016874	molecular_function	ligase activity
B	1905202	cellular_component	methylcrotonoyl-CoA carboxylase complex
C	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005929	cellular_component	cilium
C	0009374	molecular_function	biotin binding
C	0016874	molecular_function	ligase activity
C	0019856	biological_process	pyrimidine nucleobase biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
D	0005739	cellular_component	mitochondrion
D	0006552	biological_process	L-leucine catabolic process
D	0016874	molecular_function	ligase activity
D	1905202	cellular_component	methylcrotonoyl-CoA carboxylase complex
E	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005929	cellular_component	cilium
E	0009374	molecular_function	biotin binding
E	0016874	molecular_function	ligase activity
E	0019856	biological_process	pyrimidine nucleobase biosynthetic process
E	0046872	molecular_function	metal ion binding
F	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
F	0005739	cellular_component	mitochondrion
F	0006552	biological_process	L-leucine catabolic process
F	0016874	molecular_function	ligase activity
F	1905202	cellular_component	methylcrotonoyl-CoA carboxylase complex
G	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005929	cellular_component	cilium
G	0009374	molecular_function	biotin binding
G	0016874	molecular_function	ligase activity
G	0019856	biological_process	pyrimidine nucleobase biosynthetic process
G	0046872	molecular_function	metal ion binding
H	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
H	0005739	cellular_component	mitochondrion
H	0006552	biological_process	L-leucine catabolic process
H	0016874	molecular_function	ligase activity
H	1905202	cellular_component	methylcrotonoyl-CoA carboxylase complex
I	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005929	cellular_component	cilium
I	0009374	molecular_function	biotin binding
I	0016874	molecular_function	ligase activity
I	0019856	biological_process	pyrimidine nucleobase biosynthetic process
I	0046872	molecular_function	metal ion binding
J	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
J	0005739	cellular_component	mitochondrion
J	0006552	biological_process	L-leucine catabolic process
J	0016874	molecular_function	ligase activity
J	1905202	cellular_component	methylcrotonoyl-CoA carboxylase complex
K	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005929	cellular_component	cilium
K	0009374	molecular_function	biotin binding
K	0016874	molecular_function	ligase activity
K	0019856	biological_process	pyrimidine nucleobase biosynthetic process
K	0046872	molecular_function	metal ion binding
L	0004485	molecular_function	methylcrotonoyl-CoA carboxylase activity
L	0005739	cellular_component	mitochondrion
L	0006552	biological_process	L-leucine catabolic process
L	0016874	molecular_function	ligase activity
L	1905202	cellular_component	methylcrotonoyl-CoA carboxylase complex

Functional Information from PROSITE/UniProt

site_id	PS00188
Number of Residues	18
Details	BIOTIN Biotin-requiring enzymes attachment site. GQaIliLeAMKMehvVkA

Chain	Residue	Details
A	GLY631-ALA648

---

site_id	PS00867
Number of Residues	8
Details	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. FMEMNTRL

Chain	Residue	Details
A	PHE297-LEU304

---